FAM100B Activators
5-Azacytidine and Trichostatin A, which mediate changes at the genetic and chromatin levels, respectively. By inhibiting DNA methylation and histone deacetylation, these compounds can trigger a reprogramming of gene expression patterns, potentially leading to an upregulated expression of FAM100B.
Small molecule inhibitors like SB431542, LY294002, and Rapamycin, target crucial nodes within growth factor and nutrient-sensing pathways such as TGF-β, PI3K/AKT, and mTOR, respectively. Their actions can result in a broad alteration of cellular states, which includes modulation of protein synthesis and function-effects that extend to the realm of FAM100B. Similarly, SP600125 and U0126, both kinase inhibitors for JNK and MEK, can recalibrate the phosphorylation status of numerous substrates within the cell, thereby indirectly influencing the activity of FAM100B through changes in transcriptional regulation.
Moreover, compounds like DAPT, which impedes γ-secretase activity, and ion-modulating agents such as Thapsigargin and Ionomycin, that disrupt calcium homeostasis, introduce shifts in signaling dynamics that can propagate through the cell's information processing networks. These shifts could touch upon the regulatory mechanisms that control the levels or activity of FAM100B. Forskolin, which elevates intracellular cAMP, activates PKA and can lead to a cascade of phosphorylation events that might intersect with the regulatory pathways of FAM100B.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can lead to demethylation and activation of gene expression, which may upregulate FAM100B. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can cause chromatin remodeling and potentially enhance the transcription of genes, including FAM100B. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of the TGF-β receptor that could alter SMAD signaling pathways, possibly affecting FAM100B expression or activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that might influence AKT signaling and downstream protein synthesis, including that of FAM100B. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can modulate protein synthesis pathways and may impact the expression levels of FAM100B. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that could change the phosphorylation state of transcription factors and influence FAM100B expression. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
A MEK inhibitor that could alter ERK pathway signaling, potentially affecting transcription factors that regulate FAM100B. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
A γ-secretase inhibitor that can influence Notch signaling, which might affect gene expression patterns, including FAM100B. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Another MEK inhibitor that could affect ERK signaling and possibly influence the regulatory mechanisms of FAM100B expression. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
A SERCA pump inhibitor that leads to increased intracellular calcium levels, which could activate calcium-dependent signaling pathways affecting FAM100B. | ||||||