EXOD1 Activators
EXOD1 activators include a range of compounds that induce DNA damage or inhibit DNA replication and repair enzymes, influencing EXOD1 activity. The first paragraph focuses on chemical agents like Hydroxyurea, Cisplatin, and Etoposide, known for their roles in inducing DNA damage and altering DNA repair mechanisms, which might indirectly impact EXOD1 activity.
The emphasis is on other DNA-damaging agents and inhibitors of DNA repair enzymes, such as 5-Fluorouracil, Aphidicolin, and Camptothecin. Olaparib, as a PARP inhibitor, N-Ethylmaleimide, and Methyl Methanesulfonate, are considered for their to enhance DNA repair processes, wherein EXOD1 might be involved. Additionally, ATR and ATM kinase inhibitors, which play crucial roles in the DNA damage response, could also modulate EXOD1 activity in response to DNA damage and replication stress.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Inhibits ribonucleotide reductase, potentially enhancing EXOD1 activity by altering nucleotide pools and DNA repair processes. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Causes DNA crosslinking, potentially enhancing EXOD1 activity in DNA damage response and repair pathways. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Inhibits DNA topoisomerase II, potentially influencing EXOD1 activity by increasing the need for DNA repair mechanisms. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
A nucleotide analog, could enhance EXOD1 activity by inducing DNA damage and necessitating DNA repair. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Inhibits DNA polymerase, potentially enhancing EXOD1 function in DNA replication and repair. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Inhibits DNA topoisomerase I, could influence EXOD1 activity in DNA replication and repair processes. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
A PARP inhibitor, might enhance EXOD1 activity in DNA repair, particularly in base excision repair pathways. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
Alkylates cysteine residues, could indirectly affect EXOD1 activity by altering protein-protein interactions in DNA repair complexes. | ||||||
Methyl methanesulfonate | 66-27-3 | sc-250376 sc-250376A | 5 g 25 g | $56.00 $133.00 | 2 | |
Alkylating agent, could enhance EXOD1 activity by inducing DNA damage and activating DNA repair pathways. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
Inhibit ATR kinase, potentially enhancing EXOD1 function in response to replication stress and DNA damage. | ||||||