The chemical class termed Eps8L3 Activators encompasses a specific group of compounds distinguished for their ability to modulate the activity of the Eps8L3 gene. Eps8L3, or Epidermal Growth Factor Receptor Pathway Substrate 8-Like 3, is a gene encoding a protein that belongs to the Eps8 family of proteins. These proteins are known to be involved in various cellular processes, including cell proliferation, migration, and cytoskeletal remodeling. While the precise function of Eps8L3 is not fully understood, it is believed to play a role in regulating the dynamics of actin cytoskeleton and cellular morphology. Activators of Eps8L3 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Characterizing compounds as Eps8L3 Activators typically involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the Eps8L3 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through various mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for Eps8L3 gene expression, or modulating post-translational modifications of the Eps8L3 protein. Understanding the molecular mechanisms underlying Eps8L3 activation by these compounds is crucial for elucidating the roles of Eps8L3 in cellular physiology and function. Further research into Eps8L3 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of Eps8L3's function in cellular processes such as cell migration and cytoskeletal dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can affect multiple signaling pathways and potentially modulate the expression of genes like Eps8L3. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
An inhibitor of MEK1/2 that might impact downstream signaling and consequently modulate gene expression involved in cytoskeletal remodeling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that could affect actin cytoskeleton dynamics and gene expression through the PI3K/Akt pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that may alter signaling pathways affecting gene expression related to the cytoskeletal organization. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor which can influence cell shape and motility, potentially affecting the expression of genes involved in cytoskeletal regulation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that might modulate stress response pathways and impact gene expression associated with the cytoskeleton. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that could disrupt signaling pathways and influence the expression of genes related to actin dynamics. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK1 that might affect ERK pathway signaling and potentially the expression of genes like Eps8L3. | ||||||
1-β-D-Arabinofuranosylcytosine | 147-94-4 | sc-201628 sc-201628A sc-201628B sc-201628C sc-201628D | 1 g 5 g 25 g 100 g 250 g | $147.00 $258.00 $508.00 $717.00 $1432.00 | 1 | |
An inhibitor of DNA synthesis that could indirectly affect gene expression profiles, including those related to signaling pathways. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
A Rac1 inhibitor that might have an impact on gene expression by modifying actin cytoskeleton organization. | ||||||