eotaxin-3 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
Apocynin inhibits NADPH oxidase, reducing reactive oxygen species production. This action can decrease inflammatory signaling pathways that upregulate eotaxin-3 expression, thus indirectly inhibiting its activity by lowering its expression in inflamed tissues. | ||||||
Zileuton | 111406-87-2 | sc-204417 sc-204417A sc-204417B sc-204417C | 10 mg 50 mg 1 g 75 g | $84.00 $307.00 $369.00 $1254.00 | 8 | |
Zileuton, a 5-lipoxygenase inhibitor, reduces leukotriene production, a key mediator in eosinophilic inflammation. By diminishing leukotriene levels, zileuton may indirectly lower eotaxin-3 activity by attenuating the inflammatory environment that stimulates its expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin modulates multiple signaling pathways, including NF-κB, which is implicated in the transcriptional regulation of eotaxin-3. Through its anti-inflammatory properties, curcumin could indirectly reduce eotaxin-3 expression by inhibiting NF-κB activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol suppresses the activation of NF-κB and AP-1, both of which are involved in the expression of eotaxin-3. By modulating these transcription factors, resveratrol may indirectly inhibit eotaxin-3 expression in inflammatory conditions. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, inhibits the JAK/STAT pathway, which can be involved in the regulation of eotaxin-3 expression. Its anti-inflammatory effects might indirectly reduce eotaxin-3 levels by dampening the pathway that enhances its expression. | ||||||
Wogonin, S. baicalensis | 632-85-9 | sc-203313 | 10 mg | $200.00 | 8 | |
Wogonin, a flavonoid derived from Scutellaria baicalensis, inhibits the STAT3 signaling pathway, potentially affecting eotaxin-3 expression. By modulating this pathway, wogonin could indirectly decrease eotaxin-3 levels and its mediated eosinophil recruitment. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an MEK inhibitor that indirectly may influence eotaxin-3 by affecting the MAPK/ERK pathway, involved in cell proliferation and inflammatory responses. Inhibition of this pathway could lead to reduced eotaxin-3 expression in inflammatory settings. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, potentially reducing eotaxin-3 expression by inhibiting the pathway involved in stress response and inflammation. By targeting this pathway, SB203580 might indirectly suppress eotaxin-3 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, which may indirectly reduce eotaxin-3 levels by modulating the JNK pathway involved in inflammatory and stress responses. This could lead to decreased expression of eotaxin-3 in inflammatory conditions. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $40.00 | 7 | |
Andrographolide targets NF-κB, a key regulator of inflammation and eotaxin-3 expression. By inhibiting NF-κB, andrographolide could indirectly suppress eotaxin-3 levels, thereby modulating the inflammatory response. | ||||||