Date published: 2025-9-10

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EIF3S6IP激活剂

EIF3S6IP, presumably an abbreviation for "Eukaryotic Translation Initiation Factor 3 Subunit 6 Interacting Protein," would be a protein implicated in the process of translation initiation in eukaryotic cells.Translation initiation factors are crucial for the synthesis of proteins from mRNA templates. They are involved in the assembly of the ribosome, a complex molecular machine, at the start codon of mRNA molecules. In eukaryotic cells, this process is intricate and involves multiple initiation factors working together to form the pre-initiation complex.

A protein named EIF3S6IP would likely be associated with the eukaryotic initiation factor 3 (eIF3), which is one of the largest and most complex initiation factors consisting of multiple subunits. Subunit 6 of eIF3 (eIF3s6) plays a role in the stabilization of the interaction between eIF3 and other components of the translation initiation machinery. An interacting protein, such as EIF3S6IP, would conceivably modulate the function of eIF3s6 or influence the assembly, stability, or activity of the larger eIF3 complex.EIF3S6IP could potentially regulate translation initiation by affecting the binding of eIF3 to the 40S ribosomal subunit, influencing the recruitment of mRNA, or modulating the interaction with other initiation factors such as eIF1, eIF2, and eIF5. The interactions and potential regulatory roles of EIF3S6IP would be crucial for the control of protein synthesis and could play a role in cellular processes that depend on rapid changes in protein expression, such as cell growth, cell cycle progression, and response to cellular stress.

関連項目

Items 1 to 10 of 12 total

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产品名称CAS #产品编号数量价格应用排名

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

雷帕霉素可抑制 mTORC1,导致启动因子去磷酸化,从而有可能增强 EIF3S6IP 在启动翻译过程中的活性。

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

环己亚胺能阻断翻译延伸,导致启动因子的反馈上调,从而可能增加 EIF3S6IP 的活性。

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

嘌呤霉素会过早终止蛋白质合成,这可能会引起翻译启动机制(包括 EIF3S6IP)的代偿性上调。

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin 会干扰肽链的伸长,从而可能引发细胞反应,增强涉及 EIF3S6IP 的翻译启动。

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine 是一种 DNA 甲基转移酶抑制剂,可能会通过改变参与翻译的基因的甲基化状态,间接增加 EIF3S6IP 的表达。

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A 可抑制组蛋白去乙酰化酶,从而提高染色质的可及性,并上调编码 EIF3S6IP 等翻译启动因子的基因。

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

表没食子儿茶素没食子酸酯可抑制多种激酶,从而可能改变上调翻译起始成分(包括 EIF3S6IP)的信号通路。

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
18
(3)

丁酸钠是一种组蛋白去乙酰化酶抑制剂,可能会增强与翻译启动有关的基因表达,从而有可能提高 EIF3S6IP 的活性。

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

白藜芦醇能激活 SIRT1,从而导致参与翻译启动的因子去乙酰化,可能会影响 EIF3S6IP 的表达。

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

佛司可林可提高 cAMP 水平,从而刺激信号通路,加强涉及 EIF3S6IP 的翻译启动过程。