EIF3S6IP, presumably an abbreviation for "Eukaryotic Translation Initiation Factor 3 Subunit 6 Interacting Protein," would be a protein implicated in the process of translation initiation in eukaryotic cells.Translation initiation factors are crucial for the synthesis of proteins from mRNA templates. They are involved in the assembly of the ribosome, a complex molecular machine, at the start codon of mRNA molecules. In eukaryotic cells, this process is intricate and involves multiple initiation factors working together to form the pre-initiation complex.
A protein named EIF3S6IP would likely be associated with the eukaryotic initiation factor 3 (eIF3), which is one of the largest and most complex initiation factors consisting of multiple subunits. Subunit 6 of eIF3 (eIF3s6) plays a role in the stabilization of the interaction between eIF3 and other components of the translation initiation machinery. An interacting protein, such as EIF3S6IP, would conceivably modulate the function of eIF3s6 or influence the assembly, stability, or activity of the larger eIF3 complex.EIF3S6IP could potentially regulate translation initiation by affecting the binding of eIF3 to the 40S ribosomal subunit, influencing the recruitment of mRNA, or modulating the interaction with other initiation factors such as eIF1, eIF2, and eIF5. The interactions and potential regulatory roles of EIF3S6IP would be crucial for the control of protein synthesis and could play a role in cellular processes that depend on rapid changes in protein expression, such as cell growth, cell cycle progression, and response to cellular stress.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTORC1, which can lead to dephosphorylation of initiation factors, potentially enhancing the activity of EIF3S6IP in the initiation of translation. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide blocks translational elongation, causing a feedback upregulation of initiation factors, possibly increasing EIF3S6IP activity. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin prematurely terminates protein synthesis, which may cause a compensatory upregulation of the translation initiation machinery, including EIF3S6IP. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin interferes with peptide chain elongation, potentially triggering a cellular response that enhances translation initiation involving EIF3S6IP. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, may indirectly increase EIF3S6IP expression by altering the methylation status of genes involved in translation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylase, potentially increasing chromatin accessibility and upregulating genes encoding translation initiation factors like EIF3S6IP. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate inhibits multiple kinases, potentially altering signaling pathways that upregulate translation initiation components, including EIF3S6IP. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a histone deacetylase inhibitor, may enhance gene expression related to translation initiation, potentially increasing EIF3S6IP activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, which could lead to deacetylation of factors involved in translation initiation, possibly influencing EIF3S6IP expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin elevates cAMP levels, which may stimulate signaling pathways that enhance the translation initiation process involving EIF3S6IP. | ||||||