Date published: 2025-11-28

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eIF1AX Activators

EIF1AX Activators are compounds that potentially regulate EIF1AX, a protein crucial for the initiation phase of eukaryotic translation, enhancing protein synthesis. This class of compounds mainly operates by modifying various cellular pathways and processes, thereby indirectly influencing the activity of EIF1AX. For instance, compounds like Rapamycin and Torin 1, recognized as mTOR inhibitors, can modulate protein synthesis and translation initiation by acting on the mTOR signaling pathway, a critical regulator of cell growth and proliferation. These compounds, by modulating the mTOR pathway, can eventually impact the mechanisms in which EIF1AX is involved.

Likewise, compounds such as Epigallocatechin Gallate (EGCG) can influence EIF1AX activity by regulating cellular pathways related to protein synthesis, given its role as a potent antioxidant and its capability to modulate various signaling pathways. Resveratrol can modulate signaling pathways related to cell survival and apoptosis and can have implications on the activities of proteins like EIF1AX involved in protein synthesis. Additionally, substances like Caffeine, well-known for its role in blocking adenosine receptors and its consequential effects on intracellular cyclic AMP (cAMP) levels, can indirectly influence processes in which EIF1AX plays a role by modifying cellular energy levels and influencing signaling cascades related to protein synthesis.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

May increase EIF1AX activity by modulating protein synthesis pathways.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Can influence EIF1AX through mTOR inhibition, affecting protein synthesis.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Can modulate proteasome activity, possibly influencing EIF1AX stability or expression.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

By inhibiting protein synthesis, it may alter EIF1AX-mediated translation processes.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Interferes with DNA transcription, potentially impacting EIF1AX expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

By altering DNA methylation, it may impact the transcription of EIF1AX.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Its HDAC inhibitory activity can alter chromatin structure and possibly EIF1AX expression.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

May impact EIF1AX expression or function through its HDAC inhibitory activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

By modulating various cellular pathways, it can have an indirect effect on EIF1AX activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Can modulate various signaling pathways, potentially impacting EIF1AX.