Date published: 2025-11-1

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EG668379 Inhibitors

EG668379 inhibitors represent a class of chemical compounds designed to target specific biological pathways at the molecular level. These inhibitors function by binding to and inhibiting the activity of certain protein targets, often enzymes, which play critical roles in cell signaling or metabolic processes. The EG668379 inhibitors are characterized by their highly specific structural configuration, enabling them to interact precisely with their intended target proteins, thus disrupting normal function or signaling pathways. This targeted inhibition often results in the modulation of key cellular processes such as proliferation, differentiation, and cellular communication. Structurally, they tend to possess features that enhance their binding affinity, such as aromatic rings, heterocyclic elements, or polar side chains that facilitate interactions like hydrogen bonding, hydrophobic contacts, or van der Waals forces with the active sites of their targets.

The design and synthesis of EG668379 inhibitors rely heavily on structure-activity relationship (SAR) studies, which help optimize the binding affinity and selectivity of the compounds. The careful engineering of these inhibitors aims to improve their potency, ensuring that even at low concentrations, they can effectively engage their target proteins. Additionally, modifications to the core chemical structure are often made to improve stability, solubility, and bioavailability, ensuring they maintain their functional integrity within the biological milieu. EG668379 inhibitors are commonly studied in the context of their biochemical properties and how these relate to the mechanisms by which they modulate cellular activities. By understanding the molecular mechanisms of action, researchers gain insight into the broader implications of these compounds in regulating cellular function, thereby contributing to the overall field of chemical biology and the study of protein-inhibitor interactions.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Inhibits PI3K, a kinase involved in signaling pathways that can regulate secretoglobin expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Inhibits mTOR, which can affect protein synthesis including that of secretoglobins by modulating translation.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

Inhibits p38 MAPK, potentially altering inflammatory signaling pathways that can regulate secretoglobin expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Inhibits PI3K, similar to Wortmannin, affecting pathways that can regulate secretoglobin expression.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which can modify transcription factor activity that regulates secretoglobin gene expression.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Inhibits MEK, which can reduce ERK pathway signaling, potentially impacting secretoglobin expression.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$61.00
$83.00
$349.00
155
(1)

Inhibits NF-κB, which can affect the transcription of genes including those of secretoglobins.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Modulates NF-κB and other signaling pathways, potentially regulating secretoglobin gene transcription.

Sulindac

38194-50-2sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$31.00
$84.00
$147.00
3
(1)

Inhibits cyclooxygenase, which can influence inflammatory pathways that may regulate secretoglobin expression.

Eriodictyol

4049-38-1sc-263117
50 mg
$490.00
2
(0)

Modulates various signaling pathways, including those that can regulate secretoglobin expression.