EG668379 inhibitors represent a class of chemical compounds designed to target specific biological pathways at the molecular level. These inhibitors function by binding to and inhibiting the activity of certain protein targets, often enzymes, which play critical roles in cell signaling or metabolic processes. The EG668379 inhibitors are characterized by their highly specific structural configuration, enabling them to interact precisely with their intended target proteins, thus disrupting normal function or signaling pathways. This targeted inhibition often results in the modulation of key cellular processes such as proliferation, differentiation, and cellular communication. Structurally, they tend to possess features that enhance their binding affinity, such as aromatic rings, heterocyclic elements, or polar side chains that facilitate interactions like hydrogen bonding, hydrophobic contacts, or van der Waals forces with the active sites of their targets.
The design and synthesis of EG668379 inhibitors rely heavily on structure-activity relationship (SAR) studies, which help optimize the binding affinity and selectivity of the compounds. The careful engineering of these inhibitors aims to improve their potency, ensuring that even at low concentrations, they can effectively engage their target proteins. Additionally, modifications to the core chemical structure are often made to improve stability, solubility, and bioavailability, ensuring they maintain their functional integrity within the biological milieu. EG668379 inhibitors are commonly studied in the context of their biochemical properties and how these relate to the mechanisms by which they modulate cellular activities. By understanding the molecular mechanisms of action, researchers gain insight into the broader implications of these compounds in regulating cellular function, thereby contributing to the overall field of chemical biology and the study of protein-inhibitor interactions.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, a kinase involved in signaling pathways that can regulate secretoglobin expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, which can affect protein synthesis including that of secretoglobins by modulating translation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, potentially altering inflammatory signaling pathways that can regulate secretoglobin expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, similar to Wortmannin, affecting pathways that can regulate secretoglobin expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which can modify transcription factor activity that regulates secretoglobin gene expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which can reduce ERK pathway signaling, potentially impacting secretoglobin expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibits NF-κB, which can affect the transcription of genes including those of secretoglobins. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates NF-κB and other signaling pathways, potentially regulating secretoglobin gene transcription. | ||||||
Sulindac | 38194-50-2 | sc-202823 sc-202823A sc-202823B | 1 g 5 g 10 g | $31.00 $84.00 $147.00 | 3 | |
Inhibits cyclooxygenase, which can influence inflammatory pathways that may regulate secretoglobin expression. | ||||||
Eriodictyol | 4049-38-1 | sc-263117 | 50 mg | $490.00 | 2 | |
Modulates various signaling pathways, including those that can regulate secretoglobin expression. | ||||||