Date published: 2026-2-14

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EG628456 Inhibitors

Ctag2l1 Inhibitors can indirectly influence the activity of Ctag2l1 by affecting related pathways and processes. These inhibitors are diverse and act at various steps of protein and tRNA synthesis and modification. Methionine Sulfoximine, for example, may indirectly hinder the tRNA metabolic processes by affecting amino acid availability. Cycloheximide and Anisomycin disrupt protein synthesis, which could indirectly impact protein-protein interactions within the cytoplasmic EKC/KEOPS complex. Tunicamycin's role in inhibiting glycosylation may affect the stability and function of the complex, while Chloroquine's effect on lysosomal activity and autophagy could also indirectly influence cytoplasmic protein complexes.

Compounds like Puromycin, Pactamycin, Neomycin, Emetine, Harringtonine, and Homoharringtonine interact with the ribosome to inhibit protein synthesis at different stages. By disrupting protein synthesis, these compounds may prevent the formation or proper function of protein complexes, such as EKC/KEOPS, by limiting the availability of necessary protein components. Oligomycin's effects on ATP levels can have far-reaching impacts on cellular metabolism, including processes that require energy input, such as tRNA modification.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-Methionine [R,S]-Sulfoximine

15985-39-4sc-207806
1 g
$396.00
(0)

May reduce amino acid availability for tRNA charging, indirectly affecting processes Ctag2l1 could be involved in.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits protein synthesis, potentially reducing protein interaction partners of Ctag2l1 within the EKC/KEOPS complex.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Inhibits N-linked glycosylation, potentially destabilizing protein complexes associated with Ctag2l1 or proteins necessary for its function.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Affects lysosomal activity and autophagy, potentially altering the degradation of proteins that interact with Ctag2l1.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$166.00
$322.00
436
(1)

Causes premature termination of protein synthesis, potentially reducing levels of proteins that form complexes with Ctag2l1.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Prevents peptide chain elongation, potentially leading to a deficit in proteins that associate with Ctag2l1.

Oligomycin A

579-13-5sc-201551
sc-201551A
sc-201551B
sc-201551C
sc-201551D
5 mg
25 mg
100 mg
500 mg
1 g
$179.00
$612.00
$1203.00
$5202.00
$9364.00
26
(1)

Inhibits ATP synthase, potentially reducing energy for tRNA modification processes involving Ctag2l1.

Neomycin sulfate

1405-10-3sc-3573
sc-3573A
1 g
5 g
$27.00
$35.00
20
(5)

Binds to rRNA and inhibits translation, potentially affecting the synthesis of proteins that interact with Ctag2l1.

Emetine

483-18-1sc-470668
sc-470668A
sc-470668B
sc-470668C
1 mg
10 mg
50 mg
100 mg
$440.00
$900.00
$1400.00
$2502.00
(0)

Inhibits elongation at the ribosomal level, potentially affecting the synthesis of proteins necessary for Ctag2l1 function.

Harringtonin

26833-85-2sc-204771
sc-204771A
sc-204771B
sc-204771C
sc-204771D
5 mg
10 mg
25 mg
50 mg
100 mg
$250.00
$367.00
$548.00
$730.00
$980.00
30
(1)

Inhibits the elongation step of protein synthesis, potentially affecting the assembly of complexes involving Ctag2l1.