Ctag2l1 Inhibitors can indirectly influence the activity of Ctag2l1 by affecting related pathways and processes. These inhibitors are diverse and act at various steps of protein and tRNA synthesis and modification. Methionine Sulfoximine, for example, may indirectly hinder the tRNA metabolic processes by affecting amino acid availability. Cycloheximide and Anisomycin disrupt protein synthesis, which could indirectly impact protein-protein interactions within the cytoplasmic EKC/KEOPS complex. Tunicamycin's role in inhibiting glycosylation may affect the stability and function of the complex, while Chloroquine's effect on lysosomal activity and autophagy could also indirectly influence cytoplasmic protein complexes.
Compounds like Puromycin, Pactamycin, Neomycin, Emetine, Harringtonine, and Homoharringtonine interact with the ribosome to inhibit protein synthesis at different stages. By disrupting protein synthesis, these compounds may prevent the formation or proper function of protein complexes, such as EKC/KEOPS, by limiting the availability of necessary protein components. Oligomycin's effects on ATP levels can have far-reaching impacts on cellular metabolism, including processes that require energy input, such as tRNA modification.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Methionine [R,S]-Sulfoximine | 15985-39-4 | sc-207806 | 1 g | $396.00 | ||
May reduce amino acid availability for tRNA charging, indirectly affecting processes Ctag2l1 could be involved in. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits protein synthesis, potentially reducing protein interaction partners of Ctag2l1 within the EKC/KEOPS complex. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, potentially destabilizing protein complexes associated with Ctag2l1 or proteins necessary for its function. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Affects lysosomal activity and autophagy, potentially altering the degradation of proteins that interact with Ctag2l1. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
Causes premature termination of protein synthesis, potentially reducing levels of proteins that form complexes with Ctag2l1. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Prevents peptide chain elongation, potentially leading to a deficit in proteins that associate with Ctag2l1. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $179.00 $612.00 $1203.00 $5202.00 $9364.00 | 26 | |
Inhibits ATP synthase, potentially reducing energy for tRNA modification processes involving Ctag2l1. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
Binds to rRNA and inhibits translation, potentially affecting the synthesis of proteins that interact with Ctag2l1. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $440.00 $900.00 $1400.00 $2502.00 | ||
Inhibits elongation at the ribosomal level, potentially affecting the synthesis of proteins necessary for Ctag2l1 function. | ||||||
Harringtonin | 26833-85-2 | sc-204771 sc-204771A sc-204771B sc-204771C sc-204771D | 5 mg 10 mg 25 mg 50 mg 100 mg | $250.00 $367.00 $548.00 $730.00 $980.00 | 30 | |
Inhibits the elongation step of protein synthesis, potentially affecting the assembly of complexes involving Ctag2l1. | ||||||