EG545948 Inhibitors
Scgb1b20, belonging to the secretoglobin family, plays a crucial role in cellular processes associated with steroid binding, with its predicted activity localized in the extracellular region. The significance of its steroid binding activity suggests involvement in the regulation or signaling of steroid-related pathways within the extracellular space. As a member of the secretoglobin family, Scgb1b20 likely contributes to the intricate network of proteins participating in the modulation of steroid functions, potentially influencing various physiological processes. Given its extracellular localization, Scgb1b20 may act as a mediator in cellular communication, participating in the regulation of steroid-dependent signaling cascades or serving as a modulator of extracellular steroid concentrations.
The inhibition of Scgb1b20 can be achieved through direct and indirect mechanisms. Direct inhibitors, such as those targeting steroid metabolism or synthesis pathways, directly interfere with Scgb1b20's steroid binding activity, leading to disruptions in its predicted functions in the extracellular region. These inhibitors, by modulating the steroid-related processes in which Scgb1b20 is implicated, provide specific tools to investigate the intricacies of its role in steroid binding and extracellular signaling. Additionally, indirect inhibitors, including antibiotics affecting protein or RNA synthesis, influence cellular processes that may indirectly impact Scgb1b20's functions. By altering these fundamental cellular mechanisms, indirect inhibitors may contribute to a broader understanding of the pathways associated with Scgb1b20 activity and the potential crosstalk between steroid-related processes and other essential cellular functions. The identified inhibitors collectively provide valuable insights into the modulation of Scgb1b20's function and pave the way for more detailed investigations into its specific roles in steroid-related extracellular signaling events.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $63.00 $265.00 | 21 | |
Antifungal inhibiting steroid synthesis. Ketoconazole directly inhibits Scgb1b20 by interfering with steroid binding activity. This inhibition leads to a disruption in Scgb1b20's predicted functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $105.00 | 3 | |
5-alpha-reductase inhibitor affecting steroid metabolism. Finasteride directly inhibits Scgb1b20 by modulating steroid binding activity. This interference can lead to alterations in Scgb1b20's functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Metyrapone | 54-36-4 | sc-200597 sc-200597A sc-200597B | 200 mg 500 mg 1 g | $26.00 $57.00 $88.00 | 4 | |
Inhibitor of steroid 11-beta-hydroxylase. Metyrapone directly inhibits Scgb1b20 by affecting steroid binding activity. This inhibition can lead to disruptions in Scgb1b20's predicted functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Trilostane | 13647-35-3 | sc-208469 sc-208469A | 10 mg 100 mg | $228.00 $1217.00 | 2 | |
Inhibitor of 3-beta-hydroxysteroid dehydrogenase. Trilostane directly inhibits Scgb1b20 by modulating steroid binding activity. This interference can lead to alterations in Scgb1b20's functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Aminoglutethimide | 125-84-8 | sc-207280 sc-207280A sc-207280B sc-207280C | 1 g 5 g 25 g 100 g | $42.00 $146.00 $541.00 $2060.00 | 2 | |
Inhibitor of aromatase affecting steroid synthesis. Aminoglutethimide directly inhibits Scgb1b20 by interfering with steroid binding activity. This inhibition can lead to disruptions in Scgb1b20's predicted functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
Aldosterone receptor antagonist affecting steroid signaling. Spironolactone directly inhibits Scgb1b20 by modulating steroid binding activity. This interference can lead to alterations in Scgb1b20's functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Abiraterone Acetate | 154229-18-2 | sc-207240 | 5 mg | $231.00 | 1 | |
Inhibitor of CYP17A1 affecting steroid synthesis. Abiraterone directly inhibits Scgb1b20 by modulating steroid binding activity. This interference can lead to alterations in Scgb1b20's functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Exemestane | 107868-30-4 | sc-203045 sc-203045A | 25 mg 100 mg | $134.00 $411.00 | ||
Aromatase inhibitor affecting steroid synthesis. Exemestane directly inhibits Scgb1b20 by interfering with steroid binding activity. This inhibition can lead to disruptions in Scgb1b20's predicted functions in extracellular regions, potentially impacting its roles in steroid-related processes. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Antibiotic affecting RNA synthesis. Rifampin indirectly inhibits Scgb1b20 by modulating cellular processes related to RNA synthesis. The overall impact on Scgb1b20's extracellular functions depends on the specific pathways affected by Rifampin, leading to potential disruptions in steroid-related processes. | ||||||