Ear7 Inhibitors
Ear7, a gene that enables ribonuclease activity and acts upstream of or within the RNA metabolic process, plays a crucial role in cellular processes. Its involvement in RNA metabolism highlights its significance in regulating essential cellular functions. Moreover, its orthologous relationship to human RNASE2 and RNASE3, both members of the ribonuclease A family, emphasizes the evolutionary conservation of this gene.
The potential inhibition of Ear7 involves a diverse array of mechanisms targeting specific cellular pathways. These mechanisms include direct inhibition of ribonuclease activity and indirect inhibition by impacting the RNA metabolic process upstream of the gene. Chemicals like Actinomycin D interfere with transcription, disrupting the RNA metabolic process and altering the gene's involvement in ribonuclease activity. Similarly, compounds like Rifampicin and α-Amanitin indirectly influence Ear7 by targeting RNA polymerase and impacting transcription, leading to altered ribonuclease activity. These varied approaches highlight the complexity of potential Ear7 inhibition, reflecting the intricate interplay of cellular processes in which it is involved. The understanding of these mechanisms provides insights into potential strategies for inhibitnig Ear7's activity, contributing to a deeper understanding of its role in cellular functions.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits Ear7 by interfering with transcription, affecting the RNA metabolic process. This disrupts the gene's involvement in ribonuclease activity and upstream regulation of RNA metabolism. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Acts as an inhibitor by targeting bacterial RNA polymerase, influencing RNA metabolic processes. This indirectly affects Ear7's function by disrupting the RNA metabolic process upstream of the gene, leading to altered ribonuclease activity. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, impacting transcription and the RNA metabolic process. This indirect inhibition affects Ear7 by disrupting its upstream regulation of RNA metabolism, leading to altered ribonuclease activity. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Acts as an adenosine analogue, inhibiting RNA synthesis and impacting the RNA metabolic process. This indirect inhibition influences Ear7 by disrupting the upstream regulation of RNA metabolism, leading to altered ribonuclease activity. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Inhibits thymidylate synthase, disrupting DNA and RNA synthesis. This indirect inhibition affects Ear7 by influencing the RNA metabolic process and altering the gene's ribonuclease activity. | ||||||
Thiolutin | 87-11-6 | sc-200387 sc-200387A | 1 mg 5 mg | $99.00 $398.00 | 1 | |
Acts as an RNA polymerase inhibitor, impacting transcription and the RNA metabolic process. This indirect inhibition influences Ear7 by disrupting the upstream regulation of RNA metabolism, leading to altered ribonuclease activity. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, affecting de novo guanine nucleotide synthesis and the RNA metabolic process. This indirect inhibition influences Ear7 by disrupting the upstream regulation of RNA metabolism, leading to altered ribonuclease activity. | ||||||
Actinomycin V | 18865-48-0 | sc-507379 | 1 mg | $450.00 | ||
Inhibits transcription, affecting the RNA metabolic process. This indirect inhibition disrupts Ear7's involvement in ribonuclease activity by influencing the upstream regulation of RNA metabolism. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, impacting DNA replication and RNA synthesis. This indirect inhibition affects Ear7 by disrupting the RNA metabolic process and altering the gene's ribonuclease activity. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Inhibits cyclin-dependent kinases, influencing transcription and the RNA metabolic process. This indirect inhibition affects Ear7 by disrupting the upstream regulation of RNA metabolism, leading to altered ribonuclease activity. | ||||||