The chemical class known as Dysbindin 1 activators encompasses a diverse group of compounds that can influence the activity of the Dysbindin 1 protein through various indirect mechanisms within cellular signaling pathways. These activators can have a profound impact on the cellular processes that Dysbindin 1 is involved in, particularly those related to synaptic function and neuronal communication. The biochemical routes through which these activators operate can affect the modulation of Dysbindin 1, despite the lack of direct binding or interaction with the protein itself. The activators can operate by either inhibiting or stimulating enzymes upstream of Dysbindin 1, thereby altering the protein's functional state through changes in cellular signaling dynamics.
By targeting key regulatory proteins within relevant pathways, Dysbindin 1 activators can lead to an increase in the functional activity of Dysbindin 1. For example, by interacting with pathways that control the phosphorylation state of proteins, these activators can promote a cellular environment that fosters the stabilization and enhanced activity of Dysbindin 1. Additionally, through the modulation of oxidative stress and mitochondrial function, these compounds can create a cellular milieu that supports the roles of Dysbindin 1 in neuronal cells. This can include the promotion of synaptic vesicle dynamics, regulation of neurotransmitter release, and maintenance of synaptic plasticity, all of which are critical for effective neuronal communication and health. The diverse nature of these activators allows for a broad range of influences on the protein, highlighting the complex interplay between various biochemical pathways and the multifaceted roles of Dysbindin 1 in cellular physiology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium is used in the treatment of bipolar disorder and could possibly activate DTNBP1 by modulating the PI3K/Akt/mTOR pathway, associated with synaptic plasticity and implicated in psychiatric disorders. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that could possibly activate Dysbindin 1 by altering the mTOR signaling pathway, which plays a role in synaptic plasticity and neuronal development. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific PI3K inhibitor that could possibly activate Dysbindin 1 by affecting the PI3K/Akt/mTOR pathway, related to synaptic vesicle trafficking and plasticity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MAP/ERK kinase that could possibly activate Dysbindin 1 through the MAPK/ERK pathway, which is known to regulate synaptic plasticity and neuron survival. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A selective inhibitor of MEK1 and MEK2 that could possibly activate Dysbindin 1 by modulating the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A specific inhibitor of p38 MAP kinase that could possibly activate Dysbindin 1 by altering cellular responses to stress and inflammation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A specific PI3K inhibitor that could possibly activate Dysbindin 1 through effects on the PI3K/Akt/mTOR pathway. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can inhibit calcineurin and could possibly activate Dysbindin 1, since calcineurin signaling is involved in synaptic plasticity. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Another immunosuppressant that inhibits calcineurin and could possibly activate Dysbindin 1, impacting related pathways in neurons. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Acts as an antioxidant and glutathione precursor and could possibly activate Dysbindin 1 by modulating oxidative stress responses in neurons. |