ds DNA Marker Inhibitors refers to a class of chemical compounds that exhibit the ability to impede the action of certain enzymes involved in the process of DNA marker incorporation. Double-stranded DNA (ds DNA) markers are essential tools in molecular biology, commonly used to label and identify nucleic acid fragments during experiments such as gel electrophoresis. These markers help researchers visualize the size and quantity of DNA fragments. In the context of molecular biology and genetic research, the development of inhibitors targeting the incorporation of ds DNA markers is crucial for refining experimental techniques and ensuring accurate analysis.
Members of the ds DNA Marker Inhibitors class typically exert their effects by interacting with specific enzymes responsible for incorporating markers into DNA molecules. By modulating the activity of these enzymes, these inhibitors can alter the labeling process, leading to nuanced and controlled outcomes in experiments involving DNA markers. Understanding the mechanisms by which these inhibitors operate enhances the precision and reliability of molecular biology techniques, contributing to the advancement of genetic research. Researchers continually explore and refine the properties of ds DNA Marker Inhibitors to expand their utility and optimize their performance in various laboratory applications, thereby bolstering the efficiency and accuracy of experiments involving DNA markers.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethidium bromide | 1239-45-8 | sc-203735 sc-203735A sc-203735B sc-203735C | 1 g 5 g 25 g 100 g | $48.00 $150.00 $588.00 $2086.00 | 12 | |
Intercalates into DNA, disrupting DNA structure and function. | ||||||
Propidium Iodide | 25535-16-4 | sc-3541 sc-3541A | 50 mg 250 mg | $101.00 $296.00 | 168 | |
Binds to DNA by intercalating between the bases and is used in assays to differentiate dead cells. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $275.00 | 5 | |
Causes DNA cleavage, leading to strand breaks. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
Crosslinks DNA, preventing DNA replication and transcription. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Forms DNA adducts by binding to DNA, leading to DNA damage and inhibition of DNA replication. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Intercalates into DNA and interferes with DNA replication and transcription. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Inhibits topoisomerase II, leading to DNA breakage during replication. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA at the transcription initiation complex, inhibiting transcription. | ||||||
Amsacrine hydrochloride | 54301-15-4 | sc-214540 | 10 mg | $232.00 | ||
Intercalates into DNA and affects topoisomerase II activity, disrupting DNA synthesis and function. | ||||||