ds DNA Marker Antibody (HYB331-01): sc-58749

ds DNA Marker Antibody (HYB331-01) is a mouse monoclonal IgG2a antibody that detects ds DNA Marker protein of non-species reactive by western blotting (WB) and immunofluorescence (IF). anti-ds DNA Marker antibody (HYB331-01) is available as non-conjugated format, providing researchers with a reliable tool for studying DNA dynamics. Deoxyribonucleic acid (DNA) serves as the fundamental blueprint for all living organisms, encoding genetic instructions necessary for development, function, and reproduction. DNA′s structure exists as a double helix formed by two complementary strands held together by hydrogen bonds between nucleotide bases. This unique configuration protects genetic information and facilitates replication and transcription processes, where strands separate to allow access to genetic code. Double helix stability and integrity maintain genetic fidelity, and alterations can lead to mutations affecting cellular function and organismal health. ds DNA Marker (HYB331-01) antibody aids in exploring DNA behavior, interactions, and characteristics, enhancing understanding of genetic processes and implications in health and disease.

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ds DNA Marker Antibody (HYB331-01) References:

1. Mechanical stability of single DNA molecules.  |  Clausen-Schaumann, H., et al. 2000. Biophys J. 78: 1997-2007. PMID: 10733978
2. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.  |  WATSON, JD. and CRICK, FH. 1953. Nature. 171: 737-8. PMID: 13054692
3. Single-stranded adenine-rich DNA and RNA retain structural characteristics of their respective double-stranded conformations and show directional differences in stacking pattern.  |  Isaksson, J., et al. 2004. Biochemistry. 43: 15996-6010. PMID: 15609994
4. The role of heterochromatin in centromere function.  |  Pidoux, AL. and Allshire, RC. 2005. Philos Trans R Soc Lond B Biol Sci. 360: 569-79. PMID: 15905142
5. DNA mechanics.  |  Benham, CJ. and Mielke, SP. 2005. Annu Rev Biomed Eng. 7: 21-53. PMID: 16004565
6. Quadruplex DNA: sequence, topology and structure.  |  Burge, S., et al. 2006. Nucleic Acids Res. 34: 5402-15. PMID: 17012276
7. Straightforward procedure for laboratory production of DNA ladder.  |  Lan, VT., et al. 2012. J Nucleic Acids. 2012: 254630. PMID: 22496965
8. An update to DNA ladder assay for apoptosis detection.  |  Rahbar Saadat, Y., et al. 2015. Bioimpacts. 5: 25-8. PMID: 25901294
9. Individual-specific 'fingerprints' of human DNA.  |  Jeffreys, AJ., et al. Nature. 316: 76-9. PMID: 2989708
10. A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features.  |  Reis, ALM., et al. 2020. Nat Commun. 11: 3609. PMID: 32681090
11. Protein-DNA recognition.  |  Pabo, CO. and Sauer, RT. 1984. Annu Rev Biochem. 53: 293-321. PMID: 6236744
12. Biology of DNA restriction.  |  Bickle, TA. and Krüger, DH. 1993. Microbiol Rev. 57: 434-50. PMID: 8336674

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ds DNA Marker Antibody (HYB331-01) has 47 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ds DNA Marker Antibody (HYB331-01) Specifications

Alternate Product Name: ds DNA Marker

Product Clone Name: HYB331-01

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: ds DNA Marker

Epitope Species:

Product Reactivity/Detection: ds DNA

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 50 µg IgG_2a in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 47 citations in various scientific publications

Available Conjugates/Forms for ds DNA Marker Antibody (HYB331-01): N/A