Date published: 2025-9-23

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DOCK 11 Inhibitors

DOCK 11 inhibitors belong to a specific category of chemical compounds known for their ability to modulate the activity of the protein DOCK11. DOCK11, short for Dedicator of Cytokinesis 11, is a cytoplasmic protein that plays a pivotal role in regulating various cellular processes, particularly those associated with cellular signaling and cytoskeletal dynamics. Inhibitors targeting DOCK11 are designed to interact with the protein and interfere with its normal functions, thus potentially offering insights into its physiological roles and the development of new strategies for manipulating cellular processes.

These inhibitors are typically small organic molecules, characterized by their specific binding affinity for DOCK11. The mechanism of action of DOCK11 inhibitors involves their ability to bind to the active site or allosteric sites of the protein, hindering its normal interaction with other cellular components. By doing so, DOCK11 inhibitors can disrupt downstream signaling pathways and cellular processes that rely on the proper functioning of DOCK11. This chemical class plays a crucial role in advancing our understanding of cell biology and can serve as valuable tools in research to dissect the intricate mechanisms underlying cellular events mediated by DOCK11. Researchers employ DOCK11 inhibitors to gain insights into the fundamental processes governed by this protein, with potential applications spanning cell migration, cytoskeletal rearrangements, and intracellular signaling pathways

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A potent kinase inhibitor that can prevent phosphorylation steps in various signaling pathways where DOCK11 is involved.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor that can affect downstream signaling of DOCK11 by altering the PI3K/AKT pathway.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$65.00
$267.00
257
(3)

An inhibitor of JNK, which can modulate the activity of transcription factors that DOCK11 may influence.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$92.00
$223.00
30
(1)

A Src family kinase inhibitor that could disrupt signaling pathways involving DOCK11.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

A selective inhibitor of MEK that can alter signaling pathways where DOCK11 may play a role.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

A p38 MAP kinase inhibitor that might affect stress response pathways involving DOCK11.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

A PI3K inhibitor similar to LY294002, it can disturb the PI3K/AKT pathway which may be related to DOCK11 function.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor that can disrupt downstream signaling potentially affecting DOCK11-mediated processes.

Triciribine

35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$102.00
$138.00
14
(1)

An AKT inhibitor that could interfere with signaling pathways that DOCK11 may be involved in.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$47.00
$145.00
51
(1)

A broad-spectrum tyrosine kinase inhibitor that might alter multiple pathways, including those involving DOCK11.