DnaJB8 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
Geldanamycin is a known HSP90 inhibitor. DnaJB8 functions in complexes with HSP70 and HSP90, aiding in protein folding and maturation. Therefore, inhibiting HSP90 with Geldanamycin can disrupt these complexes, leading to decreased functional activity of DnaJB8. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
17-AAG is another HSP90 inhibitor. As DnaJB8 is involved in the HSP70-HSP90 complex, its functional activity can be decreased by the inhibition of HSP90 by 17-AAG. | ||||||
Radicicol | 12772-57-5 | sc-200620 sc-200620A | 1 mg 5 mg | $92.00 $333.00 | 13 | |
Radicicol is a potent HSP90 inhibitor. By inhibiting HSP90, Radicicol can disrupt the HSP70-HSP90 complexes where DnaJB8 operates, thus reducing its functional activity. | ||||||
VER 155008 | 1134156-31-2 | sc-358808 sc-358808A | 10 mg 50 mg | $203.00 $842.00 | 9 | |
VER-155008 is a HSP70 inhibitor. Since DnaJB8 functions as a co-chaperone in HSP70-HSP90 complexes, inhibiting HSP70 with VER-155008 can lead to the decreased functional activity of DnaJB8. | ||||||
MKT-077 | 147366-41-4 | sc-507514 | 5 mg | $175.00 | ||
MKT-077 is a rhodacyanine dye that targets HSP70. By inhibiting HSP70, it can decrease the functional activity of DnaJB8, which acts as a co-chaperone in the HSP70-HSP90 chaperone complex. | ||||||
Apoptosis Activator VII, Apoptozole | 1054543-47-3 | sc-221257 | 10 mg | $243.00 | 1 | |
Apoptozole is an inhibitor of HSP70. As DnaJB8 functions in the HSP70-HSP90 complex, the inhibition of HSP70 by Apoptozole can lead to a decrease in the functional activity of DnaJB8. | ||||||
JG-98 | 1456551-16-8 | sc-507517 | 5 mg | $224.00 | ||
JG-98 is an allosteric inhibitor of HSP70. Given that DnaJB8 functions as a co-chaperone in the HSP70-HSP90 complexes, inhibiting HSP70 with JG-98 can reduce the functional activity of DnaJB8. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide is an inhibitor of protein synthesis. Although it does not directly inhibit DnaJB8, it impedes the overall protein folding process, which indirectly affects the functional activity of DnaJB8, a protein chaperone. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, a post-translational modification. As DnaJB8 assists in protein folding and maturation, the inhibition of glycosylation can indirectly affect the functional activity of DnaJB8. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 is a proteasome inhibitor. As DnaJB8 might be involved in protein degradation pathways, inhibiting the proteasome can alter these pathways and indirectly affect the function of DnaJB8. | ||||||