Date published: 2026-3-3

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DLC-1 Inhibitors

DLC-1 inhibitors are a class of small molecules that specifically target and modulate the activity of the Deleted in Liver Cancer-1 (DLC-1) protein. DLC-1 is a tumor suppressor protein, meaning that it plays a crucial role in regulating cell growth and preventing the development of cancerous cells. In normal, healthy cells, DLC-1 acts as a negative regulator of cell proliferation and migration, helping to maintain tissue homeostasis. However, in many cancer types, DLC-1 is frequently inactivated or downregulated, leading to uncontrolled cell growth and metastasis. This dysregulation makes DLC-1 an attractive target for research, as DLC-1 inhibitors are designed to restore its tumor-suppressive functions. The mechanism of action of DLC-1 inhibitors typically involves binding to the DLC-1 protein or its associated signaling pathways, leading to the reactivation of its tumor-suppressive functions. By inhibiting DLC-1, these compounds halt or slow down the uncontrolled growth and invasion of cancer cells. These inhibitors represent a promising avenue in the field of oncology research, as they have the ability to address the underlying molecular mechanisms driving cancer progression and metastasis.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, found in turmeric, may influence various signaling pathways and potentially downregulate DLC-1 expression in certain cell types.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol, found in grapes and berries, might modulate gene expression and potentially reduce DLC-1 levels in some cells.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin, a flavonoid present in many fruits and vegetables, has the potential to alter gene expression, possibly affecting DLC-1.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane, found in cruciferous vegetables, may modulate cellular pathways and could influence DLC-1 expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, a soy-derived isoflavone, might modulate gene expression and cellular signaling, possibly affecting DLC-1 levels.

Silymarin group, mixture of isomers

65666-07-1sc-301806
50 g
$325.00
(0)

Silymarin, extracted from milk thistle, is known for its antioxidant properties and might influence DLC-1 expression.

Sulindac

38194-50-2sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$32.00
$86.00
$150.00
3
(1)

Sulindac may have effects on cellular signaling and gene expression, potentially impacting DLC-1.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

1,1-Dimethylbiguanide, Hydrochloride, commonly used for diabetes, has been studied for its effects on cellular signaling and gene expression, possibly affecting DLC-1.

Aspirin

50-78-2sc-202471
sc-202471A
5 g
50 g
$20.00
$42.00
4
(1)

Aspirin, a widely used NSAID, has the potential to modulate cellular pathways, possibly influencing DLC-1 expression.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine, found in coffee and tea, may have various biological effects, potentially impacting the expression of DLC-1.