Dkk-1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gallocyanine | 1562-85-2 | sc-215067 | 10 g | $49.00 | 2 | |
Gallocyanine exhibits unique properties as a Dkk-1 inhibitor, characterized by its ability to engage in specific hydrogen bonding interactions that stabilize its conformation. This compound's planar structure enhances π-π stacking with aromatic residues, influencing protein binding dynamics. Its distinct electronic properties facilitate electron transfer processes, while its solubility in polar solvents allows for effective interaction with biological membranes, impacting its overall reactivity in cellular environments. | ||||||
WAY 262611 | sc-397019 sc-397019A | 5 mg 25 mg | $131.00 $520.00 | 2 | ||
A compound that has been studied for its potential to inhibit the activity of Dickkopf-1 (Dkk-1), a protein that is involved in the regulation of the Wnt signaling pathway. Inhibition may involve interfering with the interaction between Dkk-1 and its receptors or other components of the Wnt signaling pathway. By blocking this interaction, WAY-262611 might prevent Dkk-1 from inhibiting Wnt signaling, which could have downstream effects on cellular processes regulated by the Wnt pathway. | ||||||
LGK 974 | 1243244-14-5 | sc-489380 sc-489380A | 5 mg 50 mg | $359.00 $1295.00 | 2 | |
A small molecule inhibitor that targets Porcupine, an enzyme involved in Wnt signaling. Inhibiting Porcupine disrupts the secretion and activity of DKK-1, leading to enhanced Wnt signaling. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $29.00 $38.00 | 18 | |
An anti-inflammatory drug that has been investigated for its ability to inhibit DKK-1 expression, possibly by modulating signaling pathways. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A mood stabilizer that can influence DKK-1 expression through its effects on Wnt signaling components. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A natural compound found in turmeric, curcumin has shown potential to inhibit DKK-1 expression through its effects on Wnt signaling. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressive drug that can influence DKK-1 expression indirectly through its effects on Wnt/β-catenin signaling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Used to for mood disorders, lithium can modulate Wnt signaling and potentially affect DKK-1 expression. | ||||||