DHRS6 Activators
Dehydrogenase/reductase (SDR family) member 6 (DHRS6) is an enzyme that is part of the short-chain dehydrogenases/reductases (SDR) superfamily. These enzymes are characterized by their NAD(P)(H)-dependent catalytic activity, where they participate in the oxidation and reduction of a wide variety of substrates, including steroids, prostaglandins, and retinoids. The SDR enzymes are known for their functional diversity, playing crucial roles in metabolism, development, and disease.
The specific biological role of DHRS6 remains not fully elucidated, but it is believed to be involved in the metabolism of certain lipids and steroids based on its homology to other SDR family members. The enzyme's structure typically includes a conserved Tyr-X-X-X-Lys motif, which is essential for its catalytic activity. DHRS6 may be involved in the reduction of ketones and aldehydes to their corresponding alcohols in physiological processes.The expression of DHRS6 can be tissue-specific and may be regulated by hormonal, nutritional, or environmental factors that influence cellular metabolism. Understanding the precise function of DHRS6 could have implications for metabolic diseases or conditions associated with lipid metabolism.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
May regulate gene expression through retinoic acid receptors, which bind to DNA response elements. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP levels, which may activate PKA and subsequently influence transcription factors. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Acts as a histone deacetylase inhibitor, potentially leading to changes in chromatin structure and gene activation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferases, possibly causing gene demethylation and activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor that can affect chromatin remodeling and gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Green tea polyphenol that may influence gene expression through epigenetic modifications. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid that can act on glucocorticoid response elements in gene promoters. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences GSK-3 activity, which may affect signaling pathways involved in gene transcription. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Binds to estrogen receptors, potentially affecting the transcription of certain genes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which may lead to changes in transcription factor activities. | ||||||