DHFR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DHFR monoclonal antibodies for studying dihydrofolate reductase (DHFR). DHFR Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Dihydrofolate reductase plays a central role in the folate metabolism pathway, catalyzing the reduction of dihydrofolate to tetrahydrofolate, which is essential for DNA synthesis and repair. DHFR's significance in cellular proliferation and association with various diseases, including cancer, makes it an important target for therapeutic intervention. Understanding DHFR function and regulation can provide insights into metabolic disorders and the development of antifolate drugs. Researchers can investigate DHFR expression patterns across different tissues and cellular compartments using specific detection methods. Advanced imaging techniques combined with DHFR monoclonal antibodies enable detailed visualization of protein localization and interactions. Multiple conjugation options, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), provide flexibility in experimental design. Santa Cruz Biotechnology monoclonal antibodies support the scientific community by enabling precise and reliable investigation of DHFR in biological research.