DDX56 inhibitors represent a category of chemical compounds designed to target and modulate the activity of the DDX56 protein, also known as DEAD-box RNA helicase 56. DDX56 belongs to the DEAD-box RNA helicase family, which is a group of enzymes involved in RNA metabolism and processing. These helicases play a critical role in unwinding RNA secondary structures, aiding in RNA maturation, splicing, translation, and transport. DDX56, in particular, is known for its participation in these RNA-related processes, and its activity is crucial for the proper functioning of cellular RNA molecules.
The mechanisms by which DDX56 inhibitors operate can vary depending on their chemical structures and binding properties. Some inhibitors may interact directly with DDX56, disrupting its RNA helicase activity and preventing it from unwinding RNA structures. Others may modulate the conformation or stability of DDX56, influencing its RNA-binding affinity and specificity. By inhibiting DDX56, these compounds have the potential to interfere with RNA processing, translation, and other RNA-dependent cellular processes. Ongoing research in this field aims to uncover the precise mechanisms and downstream effects of DDX56 inhibition, contributing to our understanding of its significance in cellular biology and RNA metabolism.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA at the transcription initiation complex, inhibiting RNA polymerase, which indirectly affects RNA processing and maturation, impacting DDX56 functions. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, thereby indirectly disrupting mRNA synthesis and potentially influencing DDX56-related RNA metabolic processes. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II, affecting mRNA synthesis and indirectly impacting DDX56-mediated RNA processing. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is a diterpene triepoxide that inhibits RNA Polymerase II, indirectly affecting RNA metabolism and potentially influencing DDX56 activity. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide inhibits eukaryotic initiation factors, indirectly impacting translation initiation and potentially affecting DDX56-related processes. | ||||||
Silvestrol | 697235-38-4 | sc-507504 | 1 mg | $920.00 | ||
Silvestrol, a member of the flavagline family, inhibits translation initiation by targeting eIF4A, indirectly impacting RNA metabolism related to DDX56. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine inhibits protein synthesis by blocking the initial elongation step of translation, indirectly affecting DDX56-related RNA processes. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin inhibits peptide elongation during protein synthesis, potentially impacting DDX56's role in RNA metabolism. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits eukaryotic ribosomal translocation, indirectly affecting protein synthesis and potentially influencing DDX56's function. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during translation, indirectly impacting DDX56-related processes. |