Date published: 2025-10-17

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DDX56 Inhibitors

DDX56 inhibitors represent a category of chemical compounds designed to target and modulate the activity of the DDX56 protein, also known as DEAD-box RNA helicase 56. DDX56 belongs to the DEAD-box RNA helicase family, which is a group of enzymes involved in RNA metabolism and processing. These helicases play a critical role in unwinding RNA secondary structures, aiding in RNA maturation, splicing, translation, and transport. DDX56, in particular, is known for its participation in these RNA-related processes, and its activity is crucial for the proper functioning of cellular RNA molecules.

The mechanisms by which DDX56 inhibitors operate can vary depending on their chemical structures and binding properties. Some inhibitors may interact directly with DDX56, disrupting its RNA helicase activity and preventing it from unwinding RNA structures. Others may modulate the conformation or stability of DDX56, influencing its RNA-binding affinity and specificity. By inhibiting DDX56, these compounds have the potential to interfere with RNA processing, translation, and other RNA-dependent cellular processes. Ongoing research in this field aims to uncover the precise mechanisms and downstream effects of DDX56 inhibition, contributing to our understanding of its significance in cellular biology and RNA metabolism.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D binds to DNA at the transcription initiation complex, inhibiting RNA polymerase, which indirectly affects RNA processing and maturation, impacting DDX56 functions.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

α-Amanitin inhibits RNA polymerase II, thereby indirectly disrupting mRNA synthesis and potentially influencing DDX56-related RNA metabolic processes.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

DRB inhibits RNA polymerase II, affecting mRNA synthesis and indirectly impacting DDX56-mediated RNA processing.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide is a diterpene triepoxide that inhibits RNA Polymerase II, indirectly affecting RNA metabolism and potentially influencing DDX56 activity.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

Rocaglamide inhibits eukaryotic initiation factors, indirectly impacting translation initiation and potentially affecting DDX56-related processes.

Silvestrol

697235-38-4sc-507504
1 mg
$920.00
(0)

Silvestrol, a member of the flavagline family, inhibits translation initiation by targeting eIF4A, indirectly impacting RNA metabolism related to DDX56.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$51.00
$123.00
$178.00
11
(1)

Homoharringtonine inhibits protein synthesis by blocking the initial elongation step of translation, indirectly affecting DDX56-related RNA processes.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin inhibits peptide elongation during protein synthesis, potentially impacting DDX56's role in RNA metabolism.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits eukaryotic ribosomal translocation, indirectly affecting protein synthesis and potentially influencing DDX56's function.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$163.00
$316.00
436
(1)

Puromycin causes premature chain termination during translation, indirectly impacting DDX56-related processes.