Molecular structure of Silvestrol, CAS Number: 697235-38-4
Silvestrol (CAS 697235-38-4)
CAS Number:
697235-38-4
Purity:
≥98%
Molecular Weight:
654.66
Molecular Formula:
C34H38O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Silvestrol (CAS 697235-38-4) References
- Silvestrol regulates G2/M checkpoint genes independent of p53 activity. | Mi, Q., et al. 2006. Anticancer Res. 26: 3349-56. PMID: 17094452
- Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. | Liu, T., et al. 2012. J Med Chem. 55: 8859-78. PMID: 23025805
- Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species. | Pan, L., et al. 2014. Nat Prod Rep. 31: 924-39. PMID: 24788392
- Silvestrol induces early autophagy and apoptosis in human melanoma cells. | Chen, WL., et al. 2016. BMC Cancer. 16: 17. PMID: 26762417
- Silvestrol Inhibits Chikungunya Virus Replication. | Henss, L., et al. 2018. Viruses. 10: PMID: 30380742
- Rocaglamide and silvestrol: a long story from anti-tumor to anti-coronavirus compounds. | Schulz, G., et al. 2021. Nat Prod Rep. 38: 18-23. PMID: 32699874
- The eIF4A inhibitor silvestrol sensitizes T-47D ductal breast carcinoma cells to external-beam radiotherapy. | Webb, TE., et al. 2020. Clin Transl Radiat Oncol. 24: 123-126. PMID: 32875125
- The eIF4A Inhibitor Silvestrol Blocks the Growth of Human Glioblastoma Cells by Inhibiting AKT/mTOR and ERK1/2 Signaling Pathway. | Zhang, W., et al. 2022. J Oncol. 2022: 4396316. PMID: 35677890
- In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol. | Schiffmann, S., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 36145307
- Silvestrol, a potent anticancer agent with unfavourable pharmacokinetics: Current knowledge on its pharmacological properties and future directions for the development of novel drugs. | Peron, G., et al. 2024. Biomed Pharmacother. 177: 117047. PMID: 38959604
Inhibitor of:
(eukaryotic translation initiation factor) eIF, (eukaryotic translation initiation factor) eIF1, (eukaryotic translation initiation factor) eIF2, (eukaryotic translation initiation factor) eIF5, 9130206N08Rik, A630018P17Rik, ABCE1, BIG1, C1orf77, CELF3, CELF6, CIP29, CNOT8, Coronavirus nucleocapsid, CPSF3, CPSF4, CRSP150_CRSP2, DDX23, DDX28, DDX34, DDX39, DDX3L, DDX40, DDX46, DDX47, DDX56, DDX57, DDX59, DENR, E4F1, EF-1δ, EG435337, EG666806, eIF1, eIF1AY, eIF2Bδ, eIF3α, eIF3δ, eIF3ε, eIF3M, eIF4AI, eIF4B, eIF4G, eIF4H, eIF5A1, FXR2, Gγ 1, GALK1, GCN2, GEFT, GGA2, GPATCH2, GRSF-1, GW182, hDcp2, HEXIM1, HEXIM2, hnRNP A3, hnRNP B1, hnRNP D0, hnRNP J, IMP-1, INTS2, LARP4, LARP7, Lipocalin-4, LOC100040722, MUT, NHPX, NMD3, Nova-2, NVL, Olfr239, PABPC4, Pim-3, PLRG1, Poliovirus Type 2, PPIAL4D, PRKRIP1, RBM17, RBM20, RBM22, RBM25, RBM28, RBM29, RBM35A, RBM38, RBMY1, Ribosomal Protein L15, Ribosomal Protein L22L1, RPAIN, RPL6, Rpp40, RSL24D1, SAP 145, SAP 155, SAP 62, Sec61α2, SFI1, SMNDC1, SRm300_Srrm2, SRrp35, St. Louis encephalitis, STAU2, TAFII-18, THOC1, TIA1, Tif, TRAP-α, Twinfilin-1, U11/U12 snRNP 25, U2 snRNP B′′, UTP14B, UTP15, WDR74, Y14_RBM8, ZNF265, and ZRSR1.Activator of:
C11orf59, DDX28, eIF4AIII, Paip2b, and SF4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Silvestrol, 1 mg | sc-507504 | 1 mg | $920.00 |