Cyp2c44, a member of the cytochrome P450 superfamily, is predominantly expressed in the liver and plays a vital role in drug metabolism and synthesis of cholesterol, steroids, and other lipids. It's involved in the oxidation of organic substances, including the metabolic breakdown of various drugs and the biosynthesis of endogenous compounds like cholesterol and steroids. Cyp2c44 also participates in the metabolism of arachidonic acid, a polyunsaturated fatty acid involved in cellular signaling and inflammation.
The expression of Cyp2c44 can be influenced by various factors such as genetic polymorphisms, environmental toxins. Understanding the regulation of Cyp2c44 is essential as it can impact drug efficacy and toxicity, as well as various physiological processes. Studying the inducers and inhibitors of Cyp2c44 can provide insights into optimizing pharmacotherapy and understanding the variability in drug responses among individuals. Since Cyp2c44 is involved in various metabolic pathways, any alteration in its activity can have broad implications in pharmacology and toxicology. Thus, Cyp2c44 is a significant enzyme whose activity and expression are crucial in drug metabolism and various physiological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Could enhance Cyp2c44 expression by binding to nuclear receptors and activating gene transcription. | ||||||
Omeprazole | 73590-58-6 | sc-202265 | 50 mg | $67.00 | 4 | |
A proton pump inhibitor that may indirectly influence Cyp2c44 expression due to its effect on stomach acidity and subsequent drug metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Plant-derived compounds that might modulate Cyp2c44 expression through their antioxidant properties. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $34.00 $64.00 $166.00 $281.00 | 4 | |
Dietary lipids that could influence Cyp2c44 expression and its role in fatty acid metabolism. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Compounds found in cruciferous vegetables that might influence Cyp2c44 expression related to hormone metabolism. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Phytoestrogens that might interact with Cyp2c44 expression and its role in steroid hormone metabolism. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
A compound in chili peppers that might influence Cyp2c44 expression due to its impact on metabolism and vasodilation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A polyphenol that may modulate Cyp2c44 expression due to its anti-inflammatory and antioxidant properties. | ||||||