CYFIP2 Inhibitors
CYFIP2 inhibitors belong to a distinctive chemical class that has garnered attention for its potential to modulate cellular processes by targeting a specific protein within the cell. The acronym CYFIP2 stands for Cytoplasmic FMR1 Interacting Protein 2, which is a key player in various cellular functions, particularly in the context of cellular signaling and cytoskeletal dynamics. These inhibitors are designed to selectively bind to CYFIP2, thereby impeding its normal cellular functions. The structural specificity of CYFIP2 inhibitors allows for a targeted approach in influencing cellular pathways that involve this protein.
The development of CYFIP2 inhibitors is rooted in the understanding of the protein's role in cellular processes such as actin dynamics and intracellular signaling cascades. Actin is a crucial component of the cytoskeleton, providing structural support to cells and participating in various cellular movements. CYFIP2, as an interacting partner with other cellular proteins, regulates the dynamics of actin filaments. Inhibiting CYFIP2 could potentially lead to alterations in cytoskeletal architecture and cellular signaling pathways, offering a novel means to influence cellular behavior.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, a kinase involved in the mTOR signaling pathway, which CYFIP2 is known to interact with. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is a specific inhibitor of mTOR. By inhibiting mTOR, it can indirectly affect CYFIP2's role in this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK1, a kinase involved in the ERK signaling pathway. As CYFIP2 is involved with actin cytoskeleton regulation, inhibition of this pathway can indirectly influence CYFIP2's function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, a protein involved in stress and inflammatory responses. CYFIP2's role in immune cell migration can be affected by this inhibition. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. It can indirectly affect CYFIP2 by modulating actin cytoskeleton organization and dynamics. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is a Src family kinase inhibitor. Src kinases are involved in many cellular processes, including cytoskeletal organization, which can indirectly affect the function of CYFIP2. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib is a broad-spectrum inhibitor that targets several kinases including Src family kinases. It can indirectly affect CYFIP2 function by influencing cytoskeletal organization. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Wiskostatin is a specific inhibitor of the neuronal Wiskott-Aldrich syndrome protein (N-WASP). Since CYFIP2 interacts with WASP family proteins, this can affect the action of CYFIP2. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin B disrupts actin dynamics by sequestering actin monomers. As CYFIP2 is involved in actin cytoskeleton regulation, this inhibition can indirectly influence CYFIP2's function. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D inhibits actin polymerization, affecting actin dynamics. Since CYFIP2 is involved in regulating actin cytoskeleton, this can indirectly affect CYFIP2's function. | ||||||