Cyclin M4, also known as CCNYL1 (Cyclin Y-like protein 1), is a member of the cyclin family of proteins. Cyclins are essential regulators of the cell cycle, which is the series of events that govern cell growth and division. Cyclin M4, in particular, has garnered attention for its potential role in cell cycle regulation and cellular proliferation. Activators of cyclin M4 are compounds or molecules that enhance its activity or modulate its function within cells.
Cyclin M4 activators may work through various mechanisms to influence the protein's role in cell cycle progression and other cellular processes. They can potentially affect the interactions between cyclin M4 and its binding partners, such as cyclin-dependent kinases (CDKs) or other regulatory proteins. Understanding these activators can provide insights into the broader regulatory networks in which cyclin M4 participates and its potential contributions to normal cellular functions, including cell division and proliferation. Moreover, investigating cyclin M4 activators may shed light on its roles in different cellular contexts and its implications for overall cellular homeostasis. In summary, cyclin M4 activators represent a category of compounds or molecules that modulate the activity of the cyclin M4 protein. As a member of the cyclin family, cyclin M4 is implicated in cell cycle regulation and cellular proliferation. Understanding the activation of cyclin M4 and its functional consequences can contribute to a broader comprehension of its roles in cellular physiology and cell division processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can modulate gene expression by activating nuclear receptors, potentially increasing cyclin transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This histone deacetylase inhibitor can alter chromatin structure, potentially leading to enhanced cyclin gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, it can cause hypomethylation of DNA, potentially upregulating cyclin gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which may lead to the activation of transcription factors for cyclin genes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C which can lead to the activation of pathways that increase cyclin gene transcription. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
This compound can cause DNA damage, which may induce a cellular response that includes upregulation of cyclin expression for repair processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium can affect glycogen synthase kinase-3 (GSK-3) activity, potentially influencing Wnt signaling and cyclin expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, it can lead to a more relaxed chromatin state, potentially enhancing cyclin gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can modulate several signaling pathways, potentially affecting transcription factors that regulate cyclin expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
This glucocorticoid can regulate gene expression through glucocorticoid receptor activation, potentially affecting cyclin levels. | ||||||