Date published: 2026-3-3

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cyclin B2 Activators

Cyclin B2 activators are a class of chemical compounds that specifically enhance the activity of cyclin B2, a key regulatory protein involved in the control of the cell cycle, particularly during the transition from the G2 phase to mitosis. Cyclin B2, like other cyclins, functions by forming a complex with cyclin-dependent kinases (CDKs), most notably CDK1, to regulate the progression of cells through the cell cycle. This complex is crucial for the initiation of mitosis, as it triggers the phosphorylation of various substrates that lead to the breakdown of the nuclear envelope, chromosome condensation, and spindle formation. Cyclin B2 is distinguished from other cyclins, such as cyclin B1, by its specific localization to the Golgi apparatus, where it is believed to play a role in the fragmentation of the Golgi during mitosis. The activation of cyclin B2 by specific activators typically involves the stabilization of the cyclin B2-CDK1 complex or the enhancement of cyclin B2's expression and assembly into this complex. This activation can accelerate the onset of mitosis by ensuring that the necessary phosphorylation events occur more efficiently. By promoting the activity of cyclin B2, these activators can influence the timing and fidelity of cell division, ensuring that cells progress through the cell cycle in a controlled and orderly manner. Additionally, cyclin B2 activators may impact other cellular processes associated with mitosis, such as the regulation of cytoskeletal dynamics and the proper segregation of chromosomes. Understanding how cyclin B2 activators function provides valuable insights into the mechanisms of cell cycle regulation and the role of cyclin B2 in maintaining the integrity of cell division processes. This knowledge is crucial for unraveling the complex orchestration of cellular events that occur during mitosis and for understanding how cells maintain their proliferative capacity.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is an indirect apoD activator that modulates the SIRT1 pathway. By activating SIRT1, it influences cellular processes associated with lipid metabolism and may indirectly enhance apoD expression and function.

GW501516

317318-70-0sc-202642
sc-202642A
1 mg
5 mg
$82.00
$179.00
28
(3)

GW501516 is an indirect apoD activator that targets PPARδ. By binding to PPARδ, it modulates lipid metabolism, potentially affecting apoD levels and functions indirectly.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Berberine is an indirect apoD activator that influences the AMPK pathway. By activating AMPK, it may indirectly impact apoD expression and function, although the specific mechanisms require further investigation.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$37.00
$104.00
$580.00
$1196.00
10
(1)

Oleic acid is an indirect apoD activator that modulates PPARγ. By binding to PPARγ, it influences lipid metabolism, potentially affecting apoD levels and functions indirectly.

Nicotinic Acid

59-67-6sc-205768
sc-205768A
250 g
500 g
$62.00
$124.00
1
(1)

Niacin is an indirect apoD activator that influences the GPR109A pathway. By activating GPR109A, it may indirectly impact apoD expression and function, although the specific mechanisms require further elucidation.

22(R)-hydroxycholesterol

17954-98-2sc-205106
sc-205106A
sc-205106B
1 mg
5 mg
10 mg
$110.00
$357.00
$612.00
1
(1)

22(R)-hydroxycholesterol is an indirect apoD activator that targets LXR receptors. By binding to LXRs, it modulates cholesterol homeostasis and lipid metabolism, indirectly influencing apoD expression and function.

Ciglitazone

74772-77-3sc-200902
sc-200902A
5 mg
25 mg
$104.00
$428.00
10
(1)

Ciglitazone is an indirect apoD activator that targets PPARγ. By binding to PPARγ, it modulates lipid metabolism, potentially affecting apoD levels and functions indirectly.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is an indirect apoD activator that influences the NF-κB pathway. By modulating NF-κB activity, it may indirectly impact apoD expression and function, although the specific mechanisms require further elucidation.

Nicotinamide riboside

1341-23-7sc-507345
10 mg
$411.00
(0)

Nicotinamide riboside is an indirect apoD activator that modulates the NAD+ pathway. By influencing NAD+ levels, it may indirectly impact apoD expression and function, although the specific mechanisms require further investigation.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR is an indirect apoD activator that targets the AMPK pathway. By activating AMPK, it may indirectly impact apoD expression and function, although the specific mechanisms require further investigation.