CSMD3 Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Broad-spectrum protein kinase inhibitor. Inhibits multiple kinases involved in diverse cellular processes, including cell cycle regulation and apoptosis, ultimately suppressing CSMD3 activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Irreversible inhibitor of phosphoinositide 3-kinases (PI3Ks). Disrupts PI3K signaling pathway, leading to downregulation of downstream effectors involved in cell survival and proliferation, resulting in inhibition of CSMD3. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor that interferes with mTORC1 signaling pathway. Blocks phosphorylation of p70S6K and 4E-BP1, thereby suppressing protein synthesis and cell growth, ultimately inhibiting the expression and function of CSMD3. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Selective inhibitor of p38 MAP kinase. Suppresses activation of p38 MAPK, thereby inhibiting downstream signaling pathways involved in inflammation and cellular stress response, ultimately downregulating the expression of CSMD3. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that interferes with JNK signaling pathway. Blocks phosphorylation of c-Jun, leading to inhibition of AP-1 transcription factor activity and downstream gene expression, including CSMD3, implicated in cell proliferation and survival. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that blocks PI3K/Akt signaling pathway. Inhibits Akt phosphorylation, resulting in decreased activation of downstream targets involved in cell growth and survival, ultimately suppressing CSMD3 expression and function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Highly selective inhibitor of MEK1 and MEK2. Blocks phosphorylation of ERK1/2, disrupting downstream signaling cascades involved in cell proliferation and survival, ultimately leading to inhibition of CSMD3 expression and activity. | ||||||
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $62.00 $87.00 | 4 | |
Potent inhibitor of Aurora kinases A, B, and C. Disrupts mitotic spindle assembly and chromosome segregation, inducing cell cycle arrest and apoptosis, ultimately suppressing CSMD3 expression and function. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
Selective GSK-3 inhibitor. Suppresses GSK-3β activity, leading to stabilization of β-catenin and modulation of Wnt signaling pathway, resulting in inhibition of downstream targets including CSMD3 implicated in cell proliferation and survival. | ||||||
VX-11e | 896720-20-0 | sc-507301 | 10 mg | $180.00 | ||
Potent and selective inhibitor of caspase-1 and caspase-3. Blocks apoptotic signaling pathways, preventing caspase-mediated cleavage of CSMD3 and other substrates, thereby preserving cell survival and inhibiting CSMD3 function. | ||||||