CRIP3 Activators
CRIP3 activators refer to a group of compounds capable of either directly or indirectly promoting the activity or expression of CRIP3. For example, Forskolin and BAY 60-6583 both stimulate cAMP production, which can activate specific cellular processes associated with CRIP3 upregulation. On the other hand, Ionomycin and Capsaicin highlight the role of calcium signaling. By raising intracellular calcium concentrations, they activate specific calcium-dependent mechanisms, leading to the enhancement of CRIP3 activity.
Direct kinase activation, as seen with PMA's impact on PKC and 8-Br-cGMP's influence on PKG, can stimulate specific pathways that result in CRIP3 activation. Notably, receptor-mediated pathways, such as those initiated by EGF, Bradykinin, or Epinephrine, showcase the capability of these compounds to kick-start cascades leading to the upregulation of CRIP3. Capsaicin's influence on the TRPV1 channel and its subsequent cellular effects can play a crucial role if CRIP3 activation is calcium-dependent. The roles of DAPT and Rapamycin shed light on the intricate web of cellular pathways, where activation of one pathway can lead to the modulation of another, influencing proteins like CRIP3.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, elevating cAMP levels, stimulating cellular processes that may promote CRIP3 upregulation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore that elevates intracellular calcium, activating calcium-responsive pathways that may enhance CRIP3 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Directly activates protein kinase C (PKC), which can stimulate cellular cascades leading to potential CRIP3 activation. | ||||||
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Activates Gq-coupled receptors, initiating signaling cascades that might upregulate CRIP3. | ||||||
8-Bromo-cGMP | 51116-01-9 | sc-200316 sc-200316A | 10 mg 50 mg | $102.00 $347.00 | 7 | |
A cGMP analog activating PKG, a kinase that can stimulate pathways involved in the activation of CRIP3. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Activates beta-adrenergic receptors, potentially initiating signaling cascades leading to CRIP3 upregulation. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Activates TRPV1, a channel that can initiate calcium-based pathways, potentially leading to an upregulated CRIP3. | ||||||
BAY 60-6583 | 910487-58-0 | sc-503262 | 10 mg | $210.00 | ||
Agonist for A2B adenosine receptor, promoting cAMP production, potentially stimulating cellular processes leading to CRIP3 upregulation. | ||||||
L-Quebrachitol | 642-38-6 | sc-205950 | 1 g | $148.00 | ||
Activates certain signaling pathways by modulating cellular osmolarity, potentially leading to CRIP3 activation. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
Activates the Notch signaling pathway, which might have intersecting components with CRIP3 regulation. | ||||||