CR16 Inhibitors
CR16 inhibitors are chemicals aimed at modulating the function of the protein CR16 by affecting the pathways and processes it may participate in. The chemicals selected cover a wide range of mechanisms of action, from kinase inhibition to affecting gene expression. For example, Dasatinib is a Src-family kinase inhibitor. Given that Src-family kinases play significant roles in various signaling pathways, Dasatinib can modulate pathways that CR16 is likely to be involved in. Similarly, PD98059 and U0126 are both MEK inhibitors that can disrupt the MAPK/ERK pathway, providing another angle for affecting CR16's function. INK-128, an mTOR inhibitor, has the capability to influence protein synthesis and autophagy, mechanisms that CR16 may influence.
Additionally, SP600125 focuses on inhibiting the JNK pathway, which is particularly relevant for cellular stress responses. Staurosporine, a broad kinase inhibitor, can impact multiple pathways in which CR16 might operate. Manumycin A provides an approach via Ras signaling, while 17-AAG aims to affect protein stability through Hsp90. PP2 and ZM-336372 target tyrosine kinases and c-Raf kinase, respectively, offering more ways to modulate signaling cascades that might involve CR16.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Targets Src-family kinases, potentially attenuating signaling routes that CR16 is part of, consequently altering its activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
This MEK inhibitor can disrupt the MAPK/ERK pathway, affecting CR16 if it plays a role in this signaling cascade. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits the JNK pathway, affecting stress responses that CR16 may modulate. | ||||||
Manumycin A | 52665-74-4 | sc-200857 sc-200857A | 1 mg 5 mg | $219.00 $634.00 | 5 | |
Inhibits Ras farnesyltransferase, thus affecting Ras signaling, in which CR16 may be involved. | ||||||
INK 128 | 1224844-38-5 | sc-364511 sc-364511A | 5 mg 50 mg | $321.00 $1835.00 | ||
By inhibiting mTOR, it disrupts protein synthesis and autophagy, affecting pathways that may include CR16. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Broad kinase inhibitor that can impact multiple pathways where CR16 could function. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $68.00 $312.00 | 2 | |
A CDK inhibitor which can affect cell cycle progression, potentially involving CR16. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
Targets Hsp90, which may affect the stability of proteins interacting with CR16. | ||||||
ZM 336372 | 208260-29-1 | sc-202857 | 1 mg | $47.00 | 2 | |
Inhibits c-Raf kinase, affecting the MAPK/ERK pathway, in which CR16 could be a participant. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Inhibits Src-family tyrosine kinases, potentially affecting signaling pathways that CR16 may be involved in. | ||||||