INK 128 CAS: 1224844-38-5
MF: C15H15N7O
MW: 309.33
A potent and selective TORC1/2 inhibitor.

INK 128 (CAS 1224844-38-5)

INK 128 | CAS 1224844-38-5 is rated 5.0 out of 5 by 1.
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Alternate Names: 3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application: INK 128 is a potent and selective TORC1/2 inhibitor
CAS Number: 1224844-38-5
Purity: ≥98%
Molecular Weight: 309.33
Molecular Formula: C15H15N7O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

INK 128 is a potent and selective inhibitor of TORC1 and TORC2 with broad oral antitumor activity.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (<1 mg/ml at 25 °C), DMSO (62 mg/ml at 25 °C), ethanol (2 mg/ml at 25 °C), DMSO: PBS (pH 7.2) (~0.5 mg/ml), and DMF (~1 mg/ml).
Storage :
Store at -20° C
IC50 :
mTOR: IC50 = 1 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
45375953
MDL Number :
MFCD22124893
SMILES :
CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Lou et al Lou et al. (PubMed ID 24971544) found that INK 128 inhibited the survival and growth of pancreatic cancer cells via mTORC1/2 inhibition. -SCBT Publication Review
Date published: 2015-06-29
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