Date published: 2026-5-6

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COQ2 Activators

COQ2 activators are a class of chemical compounds that have garnered significant attention in the field of mitochondrial biology and cellular energy production. The primary focus of these molecules is to modulate the activity of the COQ2 enzyme, which plays a pivotal role in the biosynthesis of coenzyme Q10 (CoQ10), also known as ubiquinone. CoQ10 is a vital component in the electron transport chain, a fundamental process within mitochondria responsible for energy production through oxidative phosphorylation. COQ2, an enzyme found within the mitochondria, catalyzes a crucial step in the biosynthetic pathway of CoQ10, making it a key factor in the maintenance of cellular energy homeostasis.

COQ2 activators are specifically designed to enhance the activity of COQ2, thereby facilitating the efficient production of CoQ10. This, in turn, supports the optimal functioning of the electron transport chain, enabling cells to generate adenosine triphosphate (ATP), the primary energy currency of the cell. While these activators do not directly participate in energy production, they indirectly contribute to cellular energy balance by promoting the synthesis of CoQ10. This class of compounds may hold promise in various areas of biological research and potentially offer insights into the fundamental mechanisms governing mitochondrial function and energy metabolism, with broader implications for cellular health and bioenergetics.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Farnesyl pyrophosphate ammonium salt

13058-04-3sc-200847
sc-200847A
1 mg
5 mg
$478.00
$1977.00
(1)

An isoprenoid precursor that activates COQ2 and facilitates CoQ biosynthesis.

Geranylgeranylpyrophosphate triammonium salt

6699-20-3sc-200849
200 µg
$122.00
(1)

Essential isoprenoid precursor that activates COQ2, vital for promoting CoQ production.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

An antioxidant that activates COQ2, safeguarding CoQ from oxidative damage.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A compound that stimulates COQ2 via sirtuin activation, potentially enhancing mitochondrial health.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$71.00
$184.00
1
(1)

A direct activator of COQ2, serving as a CoQ supplement to support mitochondrial function.

(+)-α-Tocopherol

59-02-9sc-214454
sc-214454A
sc-214454B
sc-214454C
10 g
25 g
100 g
1 kg
$43.00
$62.00
$141.00
$430.00
(1)

An antioxidant that activates COQ2, safeguarding CoQ and maintaining mitochondrial integrity.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

Complements the action of vitamin E by activating COQ2, enhancing its role as an antioxidant.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

An AMPK activator, promoting the activation of COQ2 to regulate cellular energy.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that can enhance mitochondrial quality control by activating COQ2.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

A compound that activates COQ2 through Nrf2 activation, improving cellular antioxidant defenses.