Geranylgeranylpyrophosphate triammonium salt CAS: 6699-20-3
MF: C20H36O7P2•3NH3
MW: 501.53
A geranylgeranyl-donor molecule utilized by geranylgeranyltransferase.

Geranylgeranylpyrophosphate triammonium salt (CAS 6699-20-3)

Geranylgeranylpyrophosphate triammonium salt | CAS 6699-20-3 is rated 5.0 out of 5 by 1.
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Synonym: 3,7,11,15-Tetramethyl-2,6-10,14-hexadecatetraenyl pyrophosphate NH3
Application: A geranylgeranyl-donor molecule utilized by geranylgeranyltransferase
CAS Number: 6699-20-3
Purity: ≥98%
Molecular Weight: 501.53
Molecular Formula: C20H36O7P23NH3
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Geranylgeranylpyrophosphate is a geranylgeranyl-donor molecule which is utilized by geranylgeranyltransferase for isoprenylation of target proteins.


References

1. Seabra, M.C., et al. 1992. J. Biol. Chem. 267: 14497-14503. PMID: 1321151

Formulation :
1 mg/ml in isopropanol: NH4OH (7:3)
Physical State :
Liquid
Solubility :
Soluble in water, methanol, and 100% ethanol.
Storage :
Store at -20° C
Boiling Point :
82° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44134732
SMILES :
CC(=CCCC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C)C.N.N.N

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Baetta Baetta, R. et al. (PubMed 25849951) found that atrovasratin decreased the production and release of PTX3 in human endothelial cells (hEC) through a post-transcriptional effect. Co-incubation with mevalonate and Geranylgeranyl Pyrophosphate (a geranylgeranyl-donor molecule utilized by geranylgeranyltransferase) prevented this effect. This suggests that statins may interfere with PTX3 expression in vascular cells via inhibition of protein geranylgeranylation. -SCBT Publication Review
Date published: 2015-07-01
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