Cofilin 2 Activators
Cofilin 2 activators are a class of chemical compounds that play a pivotal role in regulating the activity of cofilin 2, a critical protein involved in the dynamics of the actin cytoskeleton within cells. The actin cytoskeleton is a complex network of protein filaments that provides structural support to the cell and is essential for various cellular processes, including cell motility, division, and shape maintenance. Cofilin 2 is a member of the cofilin protein family and is primarily found in muscle cells, where it contributes to the regulation of actin filament turnover. Cofilin 2 activators, as the name suggests, are compounds that enhance the activity of cofilin 2, leading to increased actin filament severing and depolymerization.
These activators typically interact with cofilin 2 at specific binding sites, causing conformational changes that promote its ability to bind to actin filaments and facilitate their disassembly. This, in turn, influences the overall dynamics of the actin cytoskeleton, leading to alterations in cell shape and motility. Understanding the mechanisms and potential applications of cofilin 2 activators is of great interest in cell biology and biophysics, as they shed light on the intricate regulation of the actin cytoskeleton and its implications for various cellular functions. Further research into these compounds may unveil novel insights into the fundamental processes that govern cell biology and potentially open up new avenues for targeted interventions in various cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estradiol, a form of estrogen, potentially influences cofilin 2 expression by modulating hormone-responsive elements in the gene's regulatory regions. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 can impact muscle function and may influence cofilin 2 expression through its role in calcium homeostasis and cellular signaling in muscle cells. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory properties and may upregulate cofilin 2 expression as part of the cellular response to counteract stress and inflammation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, found in grapes, has antioxidant properties and may enhance cofilin 2 expression as a protective mechanism against oxidative stress in muscle cells. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major component of green tea, has anti-inflammatory effects and may upregulate cofilin 2 to modulate actin dynamics and enhance cellular resilience. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine may influence cofilin 2 expression through its stimulating effects on muscle metabolism and cellular energy balance. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, plays a role in cell differentiation and may influence cofilin 2 expression in developing and regenerating muscle tissues. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is essential for cellular function and may modulate cofilin 2 expression as part of its role in protein synthesis and cell growth, particularly in muscle cells. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium, an antioxidant, may enhance cofilin 2 expression to protect muscle cells from oxidative damage and maintain cellular function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin has anti-inflammatory and antioxidant properties and may upregulate cofilin 2 expression to enhance cellular resilience and function in muscle tissues. | ||||||