The chemical class of CLK2 activators encompasses a range of compounds that indirectly influence the activity of CLK2 through their effects on cellular signaling pathways, RNA processing, metabolism, and cell cycle regulation. These compounds, while not directly activating CLK2, can modulate the cellular environment and pathways that regulate CLK2 function and its associated processes. Compounds such as Forskolin, EGCG, Resveratrol, and Curcumin impact key signaling molecules and pathways within cells that are crucial for the regulation of kinase activity, RNA splicing, and metabolism, processes where CLK2 is involved. Forskolin, by increasing cAMP levels, and EGCG, through its influence on cellular signaling, can induce changes in kinase activity and RNA processing, potentially influencing CLK2 activity.
Furthermore, compounds like Phorbol 12-Myristate 13-Acetate (PMA), Sulforaphane, Dexamethasone, N-Acetylcysteine, Quercetin, Zinc Sulfate, Omega-3 Fatty Acids, and Vitamin D3, known for their diverse effects on cellular stress responses, redox balance, and anti-inflammatory actions, can also indirectly influence CLK2 activity. By modulating pathways related to oxidative stress, metabolism, and RNA splicing, these compounds can impact the function of CLK2 in maintaining cellular homeostasis and regulating RNA processing.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, potentially influencing CLK2 by altering signaling pathways that regulate kinase activity and RNA splicing. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects cellular signaling pathways, potentially influencing CLK2 activity by modulating pathways related to metabolism and RNA processing. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Modulates various signaling pathways, potentially influencing CLK2 activity in processes related to cell cycle regulation and RNA splicing. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Affects multiple signaling pathways, potentially modulating CLK2 activity by altering cellular processes related to metabolism and RNA splicing. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates Protein Kinase C (PKC), which can indirectly modulate CLK2 activity by influencing signaling pathways related to cell cycle and RNA processing. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Influences cellular stress responses, potentially modulating CLK2 activity by affecting pathways related to metabolism and RNA processing. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that can influence pathways related to stress response and metabolism, potentially impacting CLK2. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Known for its role in redox balance, can influence CLK2 activity by modulating oxidative stress responses and related signaling pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Acts as an antioxidant, potentially impacting CLK2 activity in processes related to cellular stress responses and RNA splicing. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essential for numerous enzymatic processes, potentially influencing CLK2 activity by modulating cellular signaling and kinase activity. |