Chromozym TRY Activators
Chromozym TRY Activators encompass a diverse array of chemical compounds that, while not directly stimulating Chromozym TRY, play a crucial role in enhancing its functional activity through the inhibition of competing proteases or the stabilization of the protein environment. Compounds like Benzamidine, Gabexate Mesilate, Aprotinin, Nafamostat Mesilate, Camostat Mesilate, and AEBSF function primarily as serine protease inhibitors. By selectively inhibiting serine proteases such as trypsin, these compounds indirectly augment Chromozym TRY activity. This enhanced activity is primarily due to the reduced proteolytic competition, allowing Chromozym TRY, produced from the PRSS1 gene, to operate more efficiently and with reduced degradation. Similarly, Leupeptin and Chymostatin act to preserve Chromozym TRY's functional form by specifically targeting trypsin and chymotrypsin, respectively, thus reducing enzymatic competition that can lead to the breakdown of Chromozym TRY.
Further contributing to the indirect activation of Chromozym TRY are compounds like E-64, Pepstatin A, Phosphoramidon, and Bestatin, which target different protease families. E-64 and Phosphoramidon, by inhibiting cysteine and metalloproteases respectively, aid in maintaining the integrity of the extracellular matrix, which in turn influences Chromozym TRY's stability and activity. Pepstatin A, an aspartic protease inhibitor, and Bestatin, an aminopeptidase inhibitor, play roles in stabilizing protein structures and reducing the degradation of peptide substrates. This stabilization and substrate preservation indirectly enhance Chromozym TRY's functional activity, as the protein faces less proteolytic degradation and a more favorable extracellular environment. Collectively, these compounds contribute to a biochemical milieu that supports and enhances the activity of Chromozym TRY, offering a multifaceted approach to promoting its functional role without directly interacting with the protein itself.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Benzamidine | 618-39-3 | sc-233933 | 10 g | $286.00 | 1 | |
Benzamidine selectively inhibits serine proteases like trypsin, which is the active form of Chromozym TRY produced by PRSS1. By inhibiting competing serine proteases, Benzamidine indirectly enhances Chromozym TRY activity by reducing proteolytic competition. | ||||||
Gabexate mesylate | 56974-61-9 | sc-215066 | 5 mg | $100.00 | ||
Gabexate Mesilate, a serine protease inhibitor, preferentially targets enzymes like trypsin. This action indirectly enhances Chromozym TRY's functional role by limiting proteolytic degradation, thus preserving its activity. | ||||||
Aprotinin | 9087-70-1 | sc-3595 sc-3595A sc-3595B | 10 mg 100 mg 1 g | $110.00 $400.00 $1615.00 | 51 | |
Aprotinin acts as an inhibitor of several serine proteases, including trypsin. Its binding to these enzymes indirectly enhances Chromozym TRY's activity by reducing enzymatic competition and promoting stability of the protein. | ||||||
Nafamostat mesylate | 82956-11-4 | sc-201307 sc-201307A | 10 mg 50 mg | $80.00 $300.00 | 4 | |
As a broad-spectrum serine protease inhibitor, Nafamostat Mesilate inhibits enzymes like trypsin. This inhibition indirectly enhances Chromozym TRY's activity by reducing protease-mediated degradation. | ||||||
Camostat mesylate | 59721-29-8 | sc-203867 sc-203867A sc-203867B sc-203867C sc-203867D sc-203867E | 10 mg 50 mg 500 mg 1 g 10 g 100 g | $42.00 $179.00 $306.00 $612.00 $2040.00 $4386.00 | 5 | |
Camostat Mesilate is a potent serine protease inhibitor, targeting enzymes such as trypsin. By inhibiting these enzymes, it indirectly enhances Chromozym TRY activity by reducing competition and degradation. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $72.00 $145.00 $265.00 $489.00 $1399.00 $99.00 | 19 | |
Leupeptin inhibits trypsin and related serine proteases. This inhibition indirectly enhances Chromozym TRY's activity by preserving its functional form and reducing protease-mediated breakdown. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
E-64, a cysteine protease inhibitor, indirectly enhances Chromozym TRY activity by reducing the degradation of extracellular matrix components, which could indirectly affect Chromozym TRY’s stability and activity. | ||||||
Phosphoramidon | 119942-99-3 | sc-201283 sc-201283A | 5 mg 25 mg | $195.00 $620.00 | 8 | |
Phosphoramidon, a metalloprotease inhibitor, indirectly enhances Chromozym TRY activity by reducing degradation of extracellular matrix components, which can influence Chromozym TRY stability and activity. | ||||||
Bestatin | 58970-76-6 | sc-202975 | 10 mg | $128.00 | 19 | |
Bestatin, an aminopeptidase inhibitor, indirectly enhances Chromozym TRY activity by reducing the breakdown of peptide substrates, leading to greater availability for Chromozym TRY activity. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $50.00 $120.00 $420.00 $834.00 $1836.00 $4896.00 | 33 | |
AEBSF, a serine protease inhibitor, indirectly enhances Chromozym TRY activity by reducing competition from other serine proteases, thus preserving its active form. | ||||||