Date published: 2026-3-3

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cGKI Antibodies

Santa Cruz Biotechnology delivers a wide array of cyclic GMP-dependent protein kinase I (cGKI) monoclonal antibodies for research in understanding biological processes. The monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). cGKI plays a crucial role in mediating the effects of nitric oxide and cyclic GMP signaling pathways, which are essential for regulating vascular smooth muscle relaxation, neuronal signaling, and various cellular processes. The proper functioning of cGKI is vital for cardiovascular health and has implications in conditions such as hypertension and heart failure. Researchers investigating cGKI can explore its involvement in signal transduction pathways and cellular responses. Understanding cGKI function helps reveal its significance in maintaining cardiovascular homeostasis and potential therapeutic interventions. Current studies focus on how cGKI influences various physiological processes and its potential as a therapeutic target. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of cGKI's role in health and disease.

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cGKI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

cGKIα Antibody (F-5)

sc-393987mouse IgM κ62-89 (h)WB, IP, IF, ELISAm, r, h
1
(3)

cGKIα/β Antibody (G-3)

sc-271766mouse IgG2b κ191-290 (h)WB, IP, IF, ELISAm, r, h
5
(6)

cGKIα/β Antibody (E-1)

sc-271765mouse IgG1 κ191-290 (h)WB, IP, IF, ELISAm, r, h
1
(2)

cGKII Antibody (D-3)

sc-393126mouse IgG2b κ1-120 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(2)

cGKII Antibody (E-7)

sc-390926mouse IgG2a κ1-120 (h)WB, IP, IF, ELISAh

new

(1)

cGKI CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

cGKIα/β CRISPR/Cas9 KO Plasmid (h)

sc-401593hGene KnockoutGFP0
(0)

cGKIα/β HDR Plasmid (h)

sc-401593-HDRhHomology Directed RepairPuromycin0
(0)

cGKII CRISPR/Cas9 KO Plasmid (h)

sc-404138hGene KnockoutGFP0
(0)

cGKII HDR Plasmid (h)

sc-404138-HDRhHomology Directed RepairPuromycin0
(0)

cGKI CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

cGKII CRISPR Activation Plasmid (h)

sc-404138-ACThGene ActivationPuro, Blast, Hygro0
(0)

cGKI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

cGKIα/β siRNA (h)

sc-35059hGene SilencingN/A0
(0)

cGKIα/β shRNA Plasmid (h)

sc-35059-SHhGene SilencingPuromycin0
(0)

cGKIα/β shRNA (h) Lentiviral Particles

sc-35059-VhGene SilencingPuromycin0
(0)

cGKIα/β siRNA (m)

sc-35060mGene SilencingN/A0
(0)

cGKIα/β shRNA Plasmid (m)

sc-35060-SHmGene SilencingPuromycin0
(0)

cGKIα/β shRNA (m) Lentiviral Particles

sc-35060-VmGene SilencingPuromycin0
(0)

cGKIα/β siRNA (r)

sc-270330rGene SilencingN/A
2
(0)

cGKIα/β shRNA Plasmid (r)

sc-270330-SHrGene SilencingPuromycin
2
(0)

cGKIα/β shRNA (r) Lentiviral Particles

sc-270330-VrGene SilencingPuromycin
2
(0)

cGKII siRNA (h)

sc-38974hGene SilencingN/A
1
(0)

cGKII shRNA Plasmid (h)

sc-38974-SHhGene SilencingPuromycin
1
(0)

cGKII shRNA (h) Lentiviral Particles

sc-38974-VhGene SilencingPuromycin
1
(0)

cGKII siRNA (m)

sc-38975mGene SilencingN/A0
(0)

cGKII shRNA Plasmid (m)

sc-38975-SHmGene SilencingPuromycin0
(0)

cGKII shRNA (m) Lentiviral Particles

sc-38975-VmGene SilencingPuromycin0
(0)

cGKII siRNA (r)

sc-270328rGene SilencingN/A0
(0)

cGKII shRNA Plasmid (r)

sc-270328-SHrGene SilencingPuromycin0
(0)

cGKII shRNA (r) Lentiviral Particles

sc-270328-VrGene SilencingPuromycin0
(0)