Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
cGKIα/β Antibody (E-1) is a high quality monoclonal cGKI alpha / beta antibody (also designated cGKIα/β antibody) suitable for the detection of the cGKI alpha / beta protein of mouse, rat and human origin. cGKIα/β Antibody (E-1) is available as the non-conjugated anti-cGKI alpha / beta antibody. cGKI (cGMP-dependent protein kinase type I), also known as PRKG1, lowers the intracellular level of calcium and is important for the relaxation of vascular smooth muscle. cGKI exists as two alternatively spliced isoforms, designated α and β, which differ only in their N-terminal sequence and function to catalyze the phosphorylation of target proteins. The cGKIα/β precursor contains one protein kinase domain, one AGC-kinase C-terminal domain and two cyclic nucleotide-binding domains. cGKII (cGMP-dependent protein kinase type II), a protein that is related to cGKI, is a major receptor of intracellular cGMP that mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino terminus and is expressed in small intestine, colon, prostate and human brain tissue. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.