The chemical class of CEACAM5 Inhibitors encompasses theoretical compounds that interact with or modulate the activity of the CEACAM5 protein. CEACAM5, known for its role in cell adhesion, signaling, and immune response modulation, can be influenced indirectly by altering the signaling pathways and molecular interactions it is involved in. The inhibitors listed above, such as kinase inhibitors and pathway-specific inhibitors, target components of signaling pathways that CEACAM5 may be part of or influence.
These inhibitors work by disrupting the molecular cascades that regulate cell proliferation, apoptosis, and metabolism, thereby indirectly impacting CEACAM5's function. For example, PI3K inhibitors like LY294002 disrupt the PI3K/Akt signaling pathway, which is crucial for many cellular processes including those in which CEACAM5 may be involved. Similarly, inhibitors targeting the MAPK/ERK pathway (e.g., PD98059) or the p38 MAPK pathway (e.g., SB203580) can alter the cellular response in a way that affects CEACAM5's role in these pathways.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor, can alter gene expression, potentially affecting CEACAM5 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor, may modify gene expression patterns including those related to CEACAM5. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, can disrupt signaling pathways that might intersect with CEACAM5 functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor, can alter the MAPK/ERK pathway, possibly influencing CEACAM5-related signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, can modify pathways potentially linked to CEACAM5 function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
JNK inhibitor, can affect signaling networks that may involve CEACAM5. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, can change cellular processes relevant to CEACAM5 signaling. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
NF-κB pathway inhibitor, can influence signaling relevant to CEACAM5 functions. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Src family kinase inhibitor, can impact pathways interacting with CEACAM5. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
EGFR inhibitor, can modulate pathways that intersect with CEACAM5-related processes. |