CCDC96 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin binds to FKBP12 and together they inhibit mTOR, which is crucial for protein synthesis and cell proliferation. As CCDC96 is involved in ciliogenesis and mTOR pathways intersect with ciliary processes, inhibition of mTOR could disrupt the functional activity of CCDC96 in ciliogenesis. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $48.00 $122.00 $432.00 $812.00 | 4 | |
WZB117 inhibits glucose transporter 1 (GLUT1), leading to decreased glucose uptake. Since ciliogenesis and the function of CCDC96 are energy-dependent processes, the reduced energy supply could indirectly impair CCDC96's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, which prevents the phosphorylation of PIP2 to PIP3, a step necessary for AKT activation. Since PI3K/AKT pathway can regulate ciliogenesis, and potentially CCDC96's role within it, LY294002 may indirectly inhibit CCDC96's function. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
PD173074 is an FGFR inhibitor. Even though FGFR proteins were excluded, this compound does not target the protein directly but inhibits its receptor's tyrosine kinase activity, which could have downstream effects on the signaling pathways that CCDC96 is involved in. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and thereby can interrupt microtubule dynamics, which is essential for ciliogenesis and the function of CCDC96 within this process. By preserving microtubule polymerization, it could indirectly hinder CCDC96's role in cilia formation. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C is a DNA crosslinker that can lead to the inhibition of DNA synthesis and cell division. Since CCDC96 is involved in ciliogenesis, processes that are affected by cell cycle dynamics, Mitomycin C might indirectly reduce the functional activity of CCDC96 by disrupting cell cycle-dependent ciliary processes. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Cyclopamine is a hedgehog signaling pathway inhibitor that suppresses smoothened (SMO) activity. The hedgehog pathway is implicated in ciliogenesis, and as such, Cyclopamine could indirectly inhibit CCDC96 by hindering a pathway critical for its function. | ||||||
Concanamycin A | 80890-47-7 | sc-202111 sc-202111A sc-202111B sc-202111C | 50 µg 200 µg 1 mg 5 mg | $65.00 $162.00 $650.00 $2550.00 | 109 | |
Concanamycin A is a specific inhibitor of V-ATPase. Disrupting the proton pump affects the acidification of organelles and can interrupt trafficking to the cilia. This could indirectly impact CCDC96's role in ciliogenesis by altering the cellular environment necessary for cilia assembly and maintenance. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts Golgi apparatus structure and function, which is key in protein sorting and trafficking to the cilia. This compound could indirectly inhibit CCDC96 by impairing ciliary protein trafficking necessary for its activity. | ||||||
rac Perhexiline Maleate | 6724-53-4 | sc-460183 | 10 mg | $184.00 | ||
Perhexiline inhibits carnitine palmitoyltransferase-1 (CPT1), which is crucial for mitochondrial fatty acid uptake and beta-oxidation. Since ciliogenesis and CCDC96's function might depend on energy balance, Perhexiline could indirectly inhibit CCDC96 by disrupting cellular energy metabolism. | ||||||