CCDC94 Inhibitors
CCDC94 Inhibitors are a class of chemical compounds that, through various biochemical mechanisms, can indirectly lead to the inhibition of the cellular coiled-coil domain containing protein 94 (CCDC94). These inhibitors target specific pathways or molecular processes that either regulate the function of CCDC94 or are required for its activity.
For example, kinase inhibitors like staurosporine and Gö6983 could prevent the phosphorylation of proteins that regulate the activity or stability of CCDC94, leading to its functional inhibition. Similarly, PI3K inhibitors such as wortmannin and LY294002 might downregulate CCDC94 by disrupting signaling pathways that are essential for its activation or expression. By blocking the PI3K pathway, these inhibitors could create a cellular environment where CCDC94 is less active due to decreased survival signaling.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that targets multiple protein kinases. By inhibiting kinase activity, it can disrupt phosphorylation events that are critical for the activation and function of various proteins. If CCDC94 function is regulated by phosphorylation, staurosporine could inhibit its function by preventing this modification. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A specific inhibitor of phosphoinositide 3-kinases (PI3K). PI3K signaling is crucial for many cellular processes, including growth and survival. Inhibition of PI3K by wortmannin could lead to cellular stress and a downregulation of proteins involved in these processes, potentially including CCDC94 if it is part of the PI3K-regulated survival pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, LY294002, blocks the signaling cascade that could otherwise lead to the activation of downstream proteins. If CCDC94 is a downstream effector in the PI3K pathway, its activity would be indirectly inhibited through the action of LY294002. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that disrupts the mTOR signaling pathway, which is involved in protein synthesis and cell growth. If CCDC94 function is linked to mTOR pathway outputs, rapamycin would reduce its activity by inhibiting the pathway. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
A protein kinase C (PKC) inhibitor which can suppress the activity of various PKC isoforms. Since PKC isoforms often regulate protein function through phosphorylation, Gö6983 could inhibit CCDC94 by preventing its necessary phosphorylation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A selective inhibitor of MEK1/2, enzymes in the MAPK/ERK pathway. By inhibiting MEK1/2, U0126 would prevent the activation of ERK, which could be necessary for CCDC94 activation if CCDC94 function is regulated by this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK (c-Jun N-terminal kinase), which is part of the stress-activated MAPK pathway. Inhibition by SP600125 could lead to a reduction in the cellular response to stress, which may include the downregulation of CCDC94 if it is involved in this response. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A specific inhibitor of p38 MAPK. The p38 pathway is involved in inflammatory responses and stress signaling. Inhibition of this pathway by SB203580 could lead to decreased activity of proteins regulated by p38 MAPK, potentially including CCDC94. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A specific inhibitor of MEK, which is upstream of ERK in the MAPK pathway. PD98059 would inhibit the activation of ERK, which could be involved in the regulatory mechanism of CCDC94, leading to its functional inhibition. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that prevents the degradation of ubiquitinated proteins, leading to the accumulation of proteins that should be degraded. If CCDC94 function depends on the proteasomal degradation of certain regulatory proteins, bortezomib could indirectly inhibit CCDC94 by altering the cellular protein balance. | ||||||