The chemical class known as CCDC81 Activators refers to a group of compounds that are characterized by their ability to upregulate the expression of the CCDC81 gene, which encodes the protein coiled-coil domain containing 81. These activators can be diverse in structure and function, sharing the common outcome of enhancing the transcription or translation of this specific gene. The mechanisms by which these activators function can vary widely, involving direct or indirect interactions with the cellular machinery responsible for gene expression. Some may bind to regulatory regions of the gene, such as enhancers or promoters, leading to increased recruitment of transcription factors and RNA polymerase, thereby enhancing transcription. Others might work by modulating the cellular environment, such as altering the epigenetic landscape around the CCDC81 gene, making it more conducive to being expressed.
Activators in this category may also exert their effects by interacting with signaling pathways that converge on the regulation of the CCDC81 gene. For instance, they might modulate the activity of kinases or phosphatases that ultimately lead to the activation of transcription factors specifically involved in CCDC81 expression. It is also possible for these compounds to affect the stability of the mRNA transcript or its translational efficiency, therefore influencing the amount of CCDC81 protein produced. The activation of the CCDC81 gene by these compounds is a result of a culmination of complex intracellular processes, which may include changes in the folding of DNA, modifications of histones, or alterations in the binding affinity of DNA-binding proteins. The specificity of CCDC81 Activators is determined by their ability to preferentially target the pathways or mechanisms controlling the CCDC81 gene without necessarily eliciting similar effects on other genes, thereby distinguishing them from broader spectrum gene expression modulators.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a DNA methyltransferase inhibitor that can change the methylation status of DNA and potentially affect gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
It is a histone deacetylase inhibitor that can alter chromatin structure and potentially increase transcription of certain genes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
This diterpene activates adenylate cyclase, increasing cAMP levels and potentially leading to the activation of cAMP response element-binding protein (CREB), which can induce gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A, it can regulate gene expression by activating nuclear retinoic acid receptors. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
As a form of estrogen, it can bind to estrogen receptors and act as a transcription factor, potentially influencing gene expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
This compound activates protein kinase C, which can lead to transcription factor activation and modulation of gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
It can affect the glycogen synthase kinase 3 (GSK-3) signaling pathway, potentially impacting gene transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Similar to trichostatin A, it is a histone deacetylase inhibitor and can influence epigenetic regulation of gene expression. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $61.00 | 17 | |
As a glucocorticoid receptor antagonist, it can affect glucocorticoid receptor-mediated gene transcription. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Known to inhibit mTOR signaling, which can have downstream effects on gene transcription. | ||||||