Date published: 2025-10-27

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CCDC66 Activators

Coiled-Coil Domain Containing 66 (CCDC66) is a protein that's encoded by the CCDC66 gene in humans. The term "coiled-coil" refers to a specific structural motif in proteins wherein alpha-helices are coiled together like the strands of a rope. This motif is involved in various functions, including protein-protein interactions and the regulation of gene expression.The CCDC66 protein is expressed in various tissues, suggesting it plays a broad role in human physiology. However, it has been particularly implicated in retinal diseases. A study in dogs identified a mutation in the CCDC66 gene associated with a form of progressive retinal atrophy, a disease that leads to blindness. Whether similar associations exist in humans remains to be explored.

In terms of cancer, there's evidence suggesting that CCDC66 may be involved in colorectal cancer progression. It has been identified as a potential biomarker, with its expression level correlating with disease stages.In summary, CCDC66 is a protein likely involved in protein-protein interactions due to its coiled-coil domain. While its exact function is not fully understood, it may play roles in retinal health and cancer progression.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG may influence gene expression and cellular signaling pathways, potentially impacting CCDC66.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol can modulate cellular signaling and gene expression, potentially affecting CCDC66.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin alters transcription factors and signaling pathways, which could influence CCDC66.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D3, through its genomic actions, might have an impact on the expression of genes like CCDC66.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid affects gene expression and could indirectly impact CCDC66.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Sulforaphane may regulate gene expression, potentially influencing CCDC66.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein, as a phytoestrogen, can modulate gene expression and might influence CCDC66.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is known for its role in regulating gene expression, which could affect CCDC66.

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$38.00
$60.00
$143.00
$306.00
$1012.00
5
(1)

This compound can modulate gene expression, potentially impacting CCDC66.

Naringenin

480-41-1sc-219338
25 g
$245.00
11
(1)

Naringenin affects cellular signaling and gene expression, which might influence CCDC66.