Coiled-Coil Domain Containing 66 (CCDC66) is a protein that's encoded by the CCDC66 gene in humans. The term "coiled-coil" refers to a specific structural motif in proteins wherein alpha-helices are coiled together like the strands of a rope. This motif is involved in various functions, including protein-protein interactions and the regulation of gene expression.The CCDC66 protein is expressed in various tissues, suggesting it plays a broad role in human physiology. However, it has been particularly implicated in retinal diseases. A study in dogs identified a mutation in the CCDC66 gene associated with a form of progressive retinal atrophy, a disease that leads to blindness. Whether similar associations exist in humans remains to be explored.
In terms of cancer, there's evidence suggesting that CCDC66 may be involved in colorectal cancer progression. It has been identified as a potential biomarker, with its expression level correlating with disease stages.In summary, CCDC66 is a protein likely involved in protein-protein interactions due to its coiled-coil domain. While its exact function is not fully understood, it may play roles in retinal health and cancer progression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG may influence gene expression and cellular signaling pathways, potentially impacting CCDC66. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can modulate cellular signaling and gene expression, potentially affecting CCDC66. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin alters transcription factors and signaling pathways, which could influence CCDC66. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3, through its genomic actions, might have an impact on the expression of genes like CCDC66. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid affects gene expression and could indirectly impact CCDC66. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane may regulate gene expression, potentially influencing CCDC66. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, as a phytoestrogen, can modulate gene expression and might influence CCDC66. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is known for its role in regulating gene expression, which could affect CCDC66. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
This compound can modulate gene expression, potentially impacting CCDC66. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin affects cellular signaling and gene expression, which might influence CCDC66. | ||||||