EGF and TGF-α are growth factors that bind to specific tyrosine kinase receptors, thereby activating a cascade of downstream signaling events, which can lead to changes in cellular behavior and the activation of a network of proteins, possibly including CCDC55. In addition, compounds such as LY294002 and Rapamycin target major signaling pathways-PI3K/AKT and mTOR, respectively-that govern critical cellular processes like growth, proliferation, and survival. These inhibitors can disrupt the normal signaling flow, leading to alterations in the activity of proteins that are part of, or regulated by, these pathways. Similarly, IBMX and A-769662 modulate cellular levels of cAMP and AMPK activity, respectively, thus affecting metabolic pathways and energy balance within the cell, which in turn can have a broad impact on protein regulation.
Furthermore, the inclusion of small molecule inhibitors like Genistein emphasizes the potential for altering kinase activity, while agents such as Calyculin A and Anisomycin demonstrate the capacity to influence protein phosphorylation and synthesis processes. The chemicals listed are representative of the diverse mechanisms through which cellular signaling can be modulated to impact the function of proteins within the cell, including proteins such as CCDC55.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Activates the insulin receptor signaling pathway, influencing glucose uptake and cellular metabolism. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, increases cAMP levels, which can enhance PKA activity and affect protein functions. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Inhibits protein tyrosine kinases, potentially altering phosphorylation cascades and affecting protein activities. | ||||||
PDGFR Tyrosine Kinase Inhibitor IV | 627518-40-5 | sc-205794 sc-205794A sc-205794B sc-205794C | 1 mg 5 mg 10 mg 50 mg | $27.00 $138.00 $257.00 $1127.00 | 2 | |
Activates the PDGF receptor, potentially influencing cell growth, survival, and angiogenesis signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, which can affect the PI3K/AKT signaling pathway and potentially the activity of related proteins. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
Activates AMPK, influencing cellular energy balance and metabolism, which can affect various protein activities. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000B sc-24000C | 10 µg 100 µg 500 µg 1 mg | $160.00 $750.00 $1400.00 $3000.00 | 59 | |
Inhibits protein phosphatases 1 and 2A, potentially altering the phosphorylation status of numerous proteins. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits protein synthesis and also activates stress-activated protein kinases, influencing protein regulation. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
Inhibitor of the TGF-β receptor, affecting the SMAD signaling pathway and potentially the activity of associated proteins. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, which can affect cell growth and metabolism pathways, potentially modulating associated protein activities. | ||||||