CCDC115, also known as Coiled-Coil Domain Containing 115, is a protein-coding gene that encodes a member of the coiled-coil domain-containing protein family. The precise function of CCDC115 is not fully understood, but it is believed to play a role in various cellular processes, including intracellular trafficking, protein-protein interactions, and possibly nucleocytoplasmic transport. Research suggests that CCDC115 may be involved in the regulation of vesicle trafficking within the endomembrane system, which is essential for the transport of proteins and lipids between cellular compartments. Additionally, CCDC115 has been implicated in the assembly and organization of protein complexes involved in intracellular signaling pathways and cellular communication.
Inhibition of CCDC115 activity can occur through various mechanisms that disrupt its normal function within the cell. One potential mechanism of inhibition involves interference with the protein-protein interactions mediated by CCDC115. By disrupting the coiled-coil domain or other functional regions of CCDC115, inhibitors may prevent its association with binding partners essential for its biological activity. Additionally, inhibition of CCDC115 expression or post-translational modifications may also impair its function and disrupt cellular processes dependent on its activity. Furthermore, small molecules or compounds that specifically target CCDC115 or its associated complexes may act as inhibitors by competitively binding to CCDC115 or blocking its interaction with other proteins or cellular components. Understanding the mechanisms of CCDC115 inhibition is crucial for elucidating its biological roles and potential implications in disease states.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts ER-Golgi trafficking, potentially affecting CCDC115's localization to the ERGIC. | ||||||
Concanamycin A | 80890-47-7 | sc-202111 sc-202111A sc-202111B sc-202111C | 50 µg 200 µg 1 mg 5 mg | $66.00 $167.00 $673.00 $2601.00 | 109 | |
Concanamycin A inhibits V-ATPase, similar to yeast Vma22p, possibly affecting CCDC115's function due to shared homology. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
N-ethylmaleimide disrupts disulfide bonds and protein function, potentially impacting CCDC115's localization and function in the ERGIC. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Golgicide A disrupts Golgi function, which could indirectly affect CCDC115's localization to the ERGIC. | ||||||
Exo1 | 461681-88-9 | sc-200752 sc-200752A | 10 mg 50 mg | $84.00 $297.00 | 4 | |
Exo1 inhibits COPI vesicle formation, potentially impacting CCDC115's association with COPI vesicles. | ||||||
Zanamivir | 139110-80-8 | sc-208495 | 1 mg | $270.00 | 6 | |
Zanamivir disrupts glycosylation processes, which may impact CCDC115's function and relevance to congenital disorders of glycosylation. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, potentially affecting CCDC115's intracellular trafficking and localization. | ||||||
Glycocholic acid | 475-31-0 | sc-218574 sc-218574A sc-218574B sc-218574C sc-218574D sc-218574E | 100 mg 1 g 5 g 10 g 50 g 100 g | $73.00 $188.00 $680.00 $1259.00 $1675.00 $3131.00 | 4 | |
GCA inhibits Golgi glycosylation, which may indirectly impact CCDC115's relevance to glycosylation disorders. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin disrupts intracellular trafficking and vesicle formation, potentially affecting CCDC115's localization to ERGIC and COPI vesicles. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K signaling, which can influence CCDC115's cellular processes and function. | ||||||