cathepsin D Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pepstatin A | 26305-03-3 | sc-45036 sc-45036A sc-45036B | 5 mg 25 mg 500 mg | $60.00 $185.00 $1632.00 | 50 | |
Pepstatin A is a potent inhibitor of aspartic proteases and may suppress the activity of cathepsin D, potentially leading to decreased protein stability and expression. | ||||||
Antipain, Dihydrochloride | 37682-72-7 | sc-291907 sc-291907A | 5 mg 25 mg | $62.00 $214.00 | 2 | |
Antipain, Dihydrochloride is a potent inhibitor of cathepsin D, distinguished by its ability to engage in specific hydrogen bonding and hydrophobic interactions with the enzyme's active site. Its unique structure facilitates the formation of a stable enzyme-inhibitor complex, altering the enzyme's conformation and disrupting its proteolytic function. Kinetic analyses reveal a non-competitive inhibition profile, highlighting its role in modulating protease activity through distinct molecular pathways. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine interferes with lysosomal function and can reduce cathepsin D expression by inhibiting its maturation process. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
While E-64 is primarily a cysteine protease inhibitor, it might indirectly reduce cathepsin D expression by affecting lysosomal protein degradation pathways. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Bafilomycin A1 inhibits vacuolar H+-ATPase, affecting lysosomal function, and could potentially decrease cathepsin D expression. | ||||||
Concanamycin A | 80890-47-7 | sc-202111 sc-202111A sc-202111B sc-202111C | 50 µg 200 µg 1 mg 5 mg | $65.00 $162.00 $650.00 $2550.00 | 109 | |
As an inhibitor of vacuolar type H+-ATPase, concanamycin A could decrease cathepsin D expression by affecting lysosomal pH and function. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Hydroxychloroquine, like chloroquine, can affect lysosomal function, potentially leading to reduced cathepsin D expression. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $140.00 $500.00 | 2 | |
U18666A disrupts lysosomal function, which may lead to decreased cathepsin D expression due to altered lysosomal protein processing. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine, a cyclin-dependent kinase inhibitor, might indirectly reduce cathepsin D expression by affecting cell cycle-related pathways. | ||||||
Sivelestat | 127373-66-4 | sc-203938 | 1 mg | $105.00 | 2 | |
Sivelestat can reduce cathepsin D activity and might lead to decreased protein expression by affecting its proteolytic processing. | ||||||