CANT1 Inhibitors
CANT1 inhibitor Suramin, with its ability to bind nucleotides, can alter the substrate availability for CANT1, thus potentially reducing its activity. Sodium Polyoxotungstate, by inhibiting enzymes structurally similar to nucleotidases, could also inhibit CANT1 indirectly. Allopurinol might lead to an increase in nucleotide levels, which could saturate CANT1 and possibly inhibit its function. ARL 67156 increases extracellular ATP levels, which might compete with CANT1's substrates, thereby affecting its activity.
Tiopronin contains thiol groups that could modify cysteine residues, which are potentially part of CANT1's active site, leading to alterations in its activity. The non-hydrolyzable nucleotide analogue β,γ-Methyleneadenosine 5'-triphosphate could potentially interact with CANT1 and inhibit its activity by serving as a decoy substrate. Levamisole, as an alkaline phosphatase inhibitor, might have off-target effects on CANT1 due to structural similarities. Clopidogrel affects ADP levels, which could indirectly modulate CANT1 activity by altering its substrate pool.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
A polysulfonated naphthylurea that inhibits various enzymes and can bind to nucleotides and nucleotide-like molecules, possibly affecting CANT1's substrate availability. | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $131.00 | ||
A xanthine oxidase inhibitor that can lead to increased nucleotide levels, potentially influencing the activity of nucleotidases such as CANT1. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
A non-hydrolyzable analogue of ATP that may affect ATPases and potentially interact with CANT1. | ||||||
Levamisole Hydrochloride | 16595-80-5 | sc-205730 sc-205730A | 5 g 10 g | $43.00 $68.00 | 18 | |
An imidazothiazole derivative that acts as an alkaline phosphatase inhibitor and might cross-react with CANT1 due to some structural analogy. | ||||||
Clopidogrel | 113665-84-2 | sc-507403 | 1 g | $122.00 | 1 | |
A prodrug that inhibits adenosine diphosphate (ADP) receptors on platelets and might influence CANT1 activity indirectly through its modulation of nucleotide levels. | ||||||
Tenofovir | 147127-20-6 | sc-204335 sc-204335A | 10 mg 50 mg | $157.00 $646.00 | 11 | |
An acyclic nucleoside phosphonate that can affect nucleotide synthesis and might indirectly influence CANT1 activity through substrate depletion. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
A nucleoside inhibitor that can impact nucleotide pools and might indirectly affect CANT1 enzyme activity. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
An inhibitor of ribonucleotide reductase that can alter deoxyribonucleotide pools, potentially influencing CANT1 activity. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
A dihydrofolate reductase inhibitor that affects nucleotide synthesis and could influence CANT1 indirectly by modulating the levels of its substrates. | ||||||