calmin Inhibitors
Calmin Inhibitors represent a class of compounds that aim to modulate the activity of the Calmin protein. In the absence of direct inhibitors, the strategic approach pivots to indirect inhibition, wherein the focus is on cellular pathways that may associate with or influence Calmin's activity. Several pathways, such as MAPK, JNK, MEK/ERK, and PI3K, play pivotal roles in cellular processes. Chemicals like SB203580, SP600125, U0126, and LY294002, target these pathways respectively, and can thereby impact proteins associated with or modulated by these pathways.
Calmin has a connection to such pathways, these chemicals can indirectly influence its function. Furthermore, mTOR signaling, JAK-STAT pathway, NF-κB signaling, and PKC pathway are also integral components of cellular processes. The inhibitors Rapamycin, AG490, BAY 11-7082, and GF109203X offer potential modulation for proteins linked with these pathways. Calmin's function or stability is linked with any of these pathways, its activity can be influenced indirectly by these inhibitors.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
If Calmin interacts with the MAPK pathway, SB203580 can be an indirect inhibitor by inhibiting p38 MAPK. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
If the JNK pathway influences Calmin, SP600125 can act as an indirect inhibitor by targeting JNK. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
By inhibiting PI3K, LY294002 can potentially modulate proteins associated with the PI3K pathway, including Calmin if linked. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Another MEK inhibitor affecting the MEK/ERK pathway and possibly influencing Calmin if interconnected. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
If Calmin's function is linked to the PI3K pathway, Wortmannin can indirectly modulate it by inhibiting PI3K. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
By targeting mTOR, Rapamycin can influence proteins related to mTOR signaling, potentially including Calmin. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
AG490 inhibits the JAK-STAT pathway. If Calmin is interconnected with this pathway, AG490 can serve as an indirect inhibitor. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
If Calmin's activity is linked to the NF-κB pathway, BAY 11-7082 can act as an indirect inhibitor by targeting NF-κB. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
This broad-spectrum kinase inhibitor can modulate multiple pathways, possibly including those influencing Calmin. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
By inhibiting PKC, GF109203X can modulate proteins involved with the PKC pathway, potentially affecting Calmin if related. | ||||||