Calcium Channel Modulators
Items 61 to 70 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1-D-3-Deoxy-phosphatidylinositol | sc-216117 sc-216117A | 100 µg 1 mg | $30.00 $77.00 | |||
1-D-3-Deoxy-phosphatidylinositol acts as a calcium channel modulator by engaging with phosphoinositide signaling pathways, influencing the activation of calcium channels through lipid bilayer interactions. Its unique structural conformation allows for specific binding to regulatory proteins, enhancing or inhibiting channel activity. This compound also alters membrane fluidity, which can affect the spatial organization of signaling complexes, thereby modulating calcium-dependent cellular processes. | ||||||
AC-265347 | 1253901-26-6 | sc-364395 sc-364395A | 5 mg 25 mg | $87.00 $370.00 | 1 | |
AC-265347 functions as a calcium channel modulator by selectively interacting with the channel's voltage-sensing domains, leading to altered gating kinetics. Its unique hydrophobic regions facilitate integration into lipid membranes, impacting channel conformational states. Additionally, AC-265347 exhibits distinct allosteric modulation, fine-tuning calcium influx through specific binding sites, which can influence downstream signaling cascades and cellular excitability. | ||||||
Phloretin | 60-82-2 | sc-3548 sc-3548A | 200 mg 1 g | $64.00 $255.00 | 13 | |
Phloretin acts as a calcium channel modulator by engaging with specific binding sites on the channel, influencing its conformational dynamics. Its unique structure allows for effective interaction with lipid bilayers, enhancing its ability to stabilize channel states. This compound also exhibits a distinctive ability to alter ion selectivity, impacting calcium permeability and influencing cellular signaling pathways. Its kinetic profile reveals a nuanced modulation of channel activity, contributing to diverse physiological effects. | ||||||
Benzydamine Hydrochloride | 132-69-4 | sc-204640 sc-204640A | 5 g 25 g | $35.00 $208.00 | ||
Benzydamine Hydrochloride functions as a calcium channel modulator through its ability to interact with the channel's lipid environment, promoting alterations in membrane fluidity. This compound exhibits unique binding characteristics that can stabilize specific channel conformations, thereby influencing ion flow. Its distinct molecular structure allows for selective interactions with various channel subtypes, potentially affecting reaction kinetics and ion transport efficiency, leading to varied cellular responses. | ||||||
Cinnarizine | 298-57-7 | sc-211095 | 100 mg | $80.00 | ||
Cinnarizine acts as a calcium channel modulator by selectively binding to the channel's intracellular domains, which alters the conformational dynamics of the channel. This interaction can enhance the channel's sensitivity to voltage changes, thereby modulating calcium influx. Its unique hydrophobic regions facilitate interactions with membrane lipids, influencing channel gating mechanisms and potentially affecting downstream signaling pathways. The compound's stereochemistry may also play a role in its specificity for different calcium channel types. | ||||||
Kavain (±) | 500-64-1 | sc-201077 sc-201077A | 50 mg 250 mg | $72.00 $300.00 | 2 | |
Kavain (+/-) functions as a calcium channel modulator by engaging with specific binding sites on the channel, leading to alterations in ion permeability. Its unique structural features allow it to stabilize channel conformations, influencing the kinetics of calcium ion flow. The compound's ability to interact with lipid bilayers may also impact membrane fluidity, further modulating channel activity. Additionally, its chiral nature could affect its interaction profiles with various calcium channel subtypes. | ||||||
Tetrandrine | 518-34-3 | sc-201492 sc-201492A | 100 mg 250 mg | $56.00 $100.00 | 9 | |
Tetrandrine acts as a calcium channel modulator by selectively binding to the channel's regulatory sites, which alters the gating mechanisms and ion conductance. Its unique polycyclic structure facilitates interactions with lipid membranes, potentially affecting the channel's microenvironment and stability. The compound exhibits distinct reaction kinetics, influencing the rate of calcium ion influx and contributing to its nuanced modulation of cellular excitability. | ||||||
Cyproheptadine hydrochloride | 969-33-5 | sc-203557 | 50 mg | $89.00 | 2 | |
Cyproheptadine hydrochloride functions as a calcium channel modulator through its ability to interact with specific binding sites on calcium channels, leading to altered ion permeability. Its unique tricyclic structure enhances its affinity for lipid bilayers, potentially influencing channel conformation and dynamics. The compound's distinct electronic properties may also affect the kinetics of calcium ion flow, providing a nuanced approach to modulating cellular signaling pathways. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
Neomycin sulfate acts as a calcium channel modulator by binding to distinct sites on calcium channels, which can influence their gating mechanisms. Its polycationic nature allows for strong electrostatic interactions with negatively charged residues on the channel, potentially stabilizing certain conformations. This modulation can alter the kinetics of calcium ion influx, impacting cellular excitability and signaling cascades. Additionally, its structural complexity may facilitate unique interactions with membrane components, further influencing channel behavior. | ||||||
Midodrine, Hydrochloride | 3092-17-9 | sc-211910 | 10 mg | $187.00 | ||
Midodrine hydrochloride functions as a calcium channel modulator through its ability to interact with specific receptor sites on calcium channels, affecting their activation and inactivation dynamics. Its unique structural features enable it to engage in selective binding, which can modify the conformational states of the channels. This interaction may lead to altered calcium ion permeability and influence downstream signaling pathways, showcasing its distinct role in cellular calcium homeostasis. | ||||||