Calcium Channel Modulators
Items 11 to 20 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NNC 55-0396 | 357400-13-6 | sc-203647A sc-203647 | 5 mg 10 mg | $245.00 $413.00 | 2 | |
NNC 55-0396 functions as a calcium channel modulator by selectively targeting L-type calcium channels, influencing their gating mechanisms. Its distinct molecular interactions stabilize the inactivated state of these channels, thereby reducing calcium ion permeability. This modulation affects intracellular calcium dynamics, leading to altered excitatory neurotransmitter release and impacting various signaling pathways. The compound's kinetic profile reveals a unique time-dependent inhibition, highlighting its potential for fine-tuning calcium-mediated processes. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
Adenosine 3',5'-cyclic monophosphate acts as a calcium channel modulator by enhancing the sensitivity of calcium channels to voltage changes. It engages in specific interactions with regulatory proteins, promoting conformational shifts that facilitate calcium influx. This compound influences second messenger systems, leading to a cascade of intracellular signaling events. Its rapid turnover and degradation kinetics allow for precise temporal control of calcium signaling, making it a key player in cellular responses. | ||||||
Protopine hydrochloride | 6164-47-2 | sc-272121 | 5 mg | $316.00 | ||
Protopine hydrochloride functions as a calcium channel modulator by selectively binding to specific sites on calcium channels, altering their permeability to calcium ions. This interaction stabilizes channel conformations, influencing the gating mechanisms and enhancing calcium ion flow. Its unique structural features allow for distinct binding affinities, impacting the kinetics of channel activation and inactivation. This modulation plays a crucial role in regulating intracellular calcium levels, affecting various cellular processes. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
Ruthenium red acts as a calcium channel modulator by interacting with the calcium channel's lipid bilayer environment, influencing channel dynamics. Its unique coordination chemistry allows it to form transient complexes with channel proteins, altering their conformational states. This interaction can lead to a reduction in calcium ion influx, affecting downstream signaling pathways. The compound's distinct redox properties also contribute to its modulation of channel activity, impacting cellular excitability and calcium homeostasis. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $45.00 $68.00 $160.00 $240.00 $410.00 | 3 | |
Magnesium sulfate anhydrous functions as a calcium channel modulator by stabilizing the conformation of channel proteins through ionic interactions. Its unique ability to chelate with specific amino acid residues alters the channel's permeability to calcium ions. This modulation affects the kinetics of calcium influx, influencing various cellular processes. Additionally, its hygroscopic nature can impact local ionic environments, further affecting channel behavior and cellular signaling pathways. | ||||||
Verapamil hydrochloride | 152-11-4 | sc-3590 sc-3590A sc-3590B | 100 mg 1 g 5 g | $50.00 $75.00 $150.00 | 22 | |
Verapamil hydrochloride acts as a calcium channel modulator by selectively binding to the L-type calcium channels, altering their gating properties. This interaction stabilizes the inactivated state of the channels, effectively reducing calcium ion flow. Its unique structure allows for specific hydrophobic interactions with channel proteins, influencing the kinetics of channel opening and closing. Additionally, the compound's solubility characteristics can affect its distribution in biological systems, impacting local ion concentrations and cellular dynamics. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $56.00 | 6 | |
Amiloride hydrochloride functions as a calcium channel modulator by interacting with epithelial sodium channels, leading to a reduction in sodium influx. Its unique molecular structure facilitates specific hydrogen bonding and electrostatic interactions with channel residues, influencing the conformational dynamics of the protein. This modulation alters the calcium-dependent signaling pathways, impacting cellular excitability and ion homeostasis. The compound's hydrophilicity enhances its solubility, affecting its bioavailability and interaction with cellular membranes. | ||||||
Amlodipine | 88150-42-9 | sc-200195 sc-200195A | 100 mg 1 g | $73.00 $163.00 | 2 | |
Amlodipine acts as a calcium channel modulator by selectively binding to L-type calcium channels, stabilizing their inactive state. This interaction alters the channel's gating kinetics, reducing calcium ion permeability and influencing intracellular calcium levels. Its unique lipophilic character enhances membrane penetration, allowing for effective modulation of vascular smooth muscle tone. Additionally, the compound exhibits distinct stereochemistry, which may affect its binding affinity and channel selectivity. | ||||||
CCR2 Antagonist | 445479-97-0 | sc-202525 | 5 mg | $299.00 | 34 | |
CCR2 Antagonist functions as a calcium channel modulator by interacting with specific receptor sites, leading to altered calcium ion flux across cellular membranes. This compound exhibits unique binding dynamics that influence the conformational state of calcium channels, thereby modulating their activity. Its distinct molecular structure allows for selective interactions with various signaling pathways, potentially impacting downstream cellular responses. The compound's hydrophobic regions facilitate its integration into lipid bilayers, enhancing its modulatory effects. | ||||||
PSTAIRE peptide | sc-3142 | 0.5 mg | $95.00 | |||
PSTAIRE peptide acts as a calcium channel modulator by selectively binding to calcium channel subunits, influencing their gating mechanisms. Its unique amino acid sequence promotes specific interactions with channel proteins, altering their conformational dynamics. This modulation affects calcium influx, impacting cellular excitability and signaling cascades. The peptide's structural flexibility allows it to adapt to different channel conformations, enhancing its regulatory potential in various cellular environments. | ||||||