C4orf18 inhibitors represent a class of chemical entities tailored to modulate the activity of a protein encoded by the C4orf18 gene, which is located on chromosome 4 and initially characterized as an open reading frame (orf). The proteins encoded by genes such as C4orf18 often have elusive functions, and the development of specific inhibitors is a strategy used by researchers to understand the biological role of such proteins. Inhibitors targeting C4orf18 would bind to the protein in a manner that affects its normal function, providing insights into the protein's role within the cell. These chemical inhibitors would be the result of extensive research into the protein's structure, its interactions with other cellular constituents, and its participation in cellular processes. Detailed knowledge of the protein's three-dimensional structure and active sites, if it has enzymatic activity, would be crucial in designing molecules that can bind to C4orf18 and inhibit its function.
The pursuit of C4orf18 inhibitors would typically start with an in-depth structural and functional analysis of the C4orf18 protein. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, or cryo-electron microscopy could be utilized to gain a high-resolution image of the protein's structure, revealing potential druggable pockets or binding sites. Alongside structural studies, functional assays would be crucial in determining the protein's role in the cell, whether it is involved in enzymatic reactions, cellular signaling, or other regulatory mechanisms. Once the structure and function of C4orf18 are elucidated, the information can be used to inform the design of specific inhibitors that can modulate the protein's activity.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent, broad-spectrum kinase inhibitor that could non-selectively inhibit the activity of many kinases, including hypothetical Golgi-associated kinases. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $126.00 $210.00 $488.00 | 19 | |
K252a is an indolocarbazole that acts as a kinase inhibitor, affecting a range of kinases by inhibiting their ATP binding site. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that interferes with the phosphorylation processes essential for kinase signaling. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib is a Src-family kinase inhibitor that could affect the function of a wide variety of kinases due to the conserved nature of the ATP binding site. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Imatinib targets certain tyrosine kinases, and while it is specific for certain kinases, it could also affect other kinases. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that might impact kinase signaling pathways associated with the Golgi. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK) and might affect other kinases with similar ATP binding sites. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of MEK, a kinase that acts in the MAPK/ERK pathway, which could indirectly affect Golgi-associated kinases. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that might influence the activity of Golgi-associated kinases through interconnected pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that, by altering PI3K activity, could potentially affect Golgi-associated kinase signaling. |